2-Chloro-N,N-diethyl-2,2-difluoroacetamide CAS 52801-33-9
| CAS No. | 52801-33-9 |
| Molecular Formula | C6H10ClF2NO |
| Molecular Weight | 185.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 185.60 g/mol gives 2-Chloro-N,N-diethyl-2,2-difluoroacetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-N,N-diethyl-2,2-difluoroacetamide (CAS 52801-33-9) is a high-purity analytical reference standard with the molecular formula C6H10ClF2NO and a molecular weight of 185.60 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-N,N-diethyl-2,2-difluoroacetamide is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 185.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-N,N-diethyl-2,2-difluoroacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10ClF2NO |
| Molecular Weight | 185.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-chloro-6-fluoro-1H-benzo[d]imidazol-5-amine (CAS 117275-51-1)
- 5-Chloro-7-fluoro-1H-benzo[d]imidazol-6-amine (CAS 1426290-07-4)
- 4-Chloro-5-fluoro-1H-indazol-3-amine (CAS 1715913-00-0)
- (2-Chloro-5-fluoro-yrimidin-4-yl)prop-2-ynylamine (CAS 477592-83-9)
- 3-Chloro-4-fluoro-1H-indazol-6-amine (CAS 885520-15-0)
- 3-Chloro-6-fluoro-1h-indazol-5-amine (CAS 864082-73-5)
- 2-(6-Chloro-5-methylpyridin-3-yl)acetic acid (CAS 1000546-06-4)
- 2-(2-chloro-6-methylpyridin-3-yl)acetic acid (CAS 1000567-19-0)
Recommended Standards
- 4-Amino-3-chloro-6-fluoroindazole (CAS 885522-92-9)
- 3-(chloromethyl)-5-(1,1-difluoroethyl)isoxazole (CAS 861135-78-6)
- 2-Oxooxazolidine-3-sulfonyl chloride (CAS 710286-63-8)
- 2-(6-chloro-2-methylpyridin-3-yl)acetic acid (CAS 1000568-04-6)
- 5-Bromo-2-chloro-6-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227269-09-1)
- 5-Bromo-2-[(2-chlorobenzyl)oxy]benzoyl chloride (CAS 1160250-23-6)
- 2-Bromo-4-chloro-6-fluorobenzothiazole (CAS 210834-97-2)
- 5-Chloro-N-(4-methoxynaphthalen-1-yl)thiophene-2-carboxamide (CAS 330678-00-7)
- 5-Chloro-2-cyclopropoxybenzoic acid (CAS 959749-03-2)
- 1-Bromo-3-(2,2-difluoropropyl)benzene (CAS 1099598-19-2)
- Isopropyl 2-amino-4-(3-chloro-4-nitrophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS 939894-04-9)
- (1-Amino-2-hydroxyethyl)(2-ethylhexyl)sulfamic acid (CAS 99948-85-3)
- 4-Propylheptanoic acid (CAS 6796-27-6)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com