4-[2-(cyanomethyl)-1,3-thiazol-4-yl]benzonitrile CAS 528522-91-0
| CAS No. | 528522-91-0 |
| Molecular Formula | C12H7N3S |
| Molecular Weight | 225.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[2-(cyanomethyl)-1,3-thiazol-4-yl]benzonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[2-(cyanomethyl)-1,3-thiazol-4-yl]benzonitrile (CAS 528522-91-0) is a high-purity analytical reference standard with the molecular formula C12H7N3S and a molecular weight of 225.27 g/mol.
The molecular framework of 4-[2-(cyanomethyl)-1,3-thiazol-4-yl]benzonitrile (C12H7N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-[2-(cyanomethyl)-1,3-thiazol-4-yl]benzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7N3S |
| Molecular Weight | 225.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related cyanomethyl Standards
- 2-((Cyanomethyl)sulfonyl)benzoic acid (CAS 243984-87-4)
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- 1-Boc-3-(cyanomethyl)piperidine (CAS 948015-72-3)
- 1-Boc-4-(cyanomethyl)piperidine (CAS 256411-39-9)
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- 2-Cyanomethyl-morpholine-4-carboxylic acid tert-butyl ester (CAS 259180-69-3)
Recommended Standards
- 3-(tert-Butyl)indeno[1,2-c]pyrazol-4(3aH)-one (CAS 6287-80-5)
- 4-Amino-3-(m-tolyl)-2,3-dihydro-1,2,5-thiadiazole 1,1-dioxide (CAS 425646-68-0)
- 3-((Methylamino)methyl)-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 807283-74-5)
- 6-Fluoro-N,N-dimethyl-2-(piperazin-1-yl)pyrimidin-4-amine (CAS 675588-46-2)
- (2-Oxaspiro[4.4]nonan-3-yl)methanol (CAS 2059970-64-6)
- ethyl 2,2-difluoro-3-(3-formyl-5,6,7,8-tetrahydroindolizin-8-yl)propanoate (CAS 2766353-03-9)
- Biotinyl-(Gln1)-Gastrin I (human) (CAS 1815618-03-1)
- 3-Ethyl-1-[2-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea (CAS 854074-34-3)
- 2-((3-(((2,3-Dihydro-2-oxo-1H-benzimidazol-5-yl)amino)-carbonyl)-2-hydroxy-1-naphthalenyl)-azo)-benzoicacid methylester (CAS 6985-92-8)
- (R)-4-Ethoxy-2-(methylthio)-6-(pyrrolidin-3-yloxy)pyrimidine hydrochloride (CAS 1353995-17-1)
- Cilostamide, 98% (CAS 68550-75-4)
- tert-Butyl 8-(4-methylpiperidine-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate (CAS 910797-04-5)
- 4-nitrochalcone (CAS 1222-98-6)
- Fas C- Terminal Tripeptide (CAS 189109-90-8)
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