6-Fluoro-N,N-dimethyl-2-(piperazin-1-yl)pyrimidin-4-amine CAS 675588-46-2
| CAS No. | 675588-46-2 |
| Molecular Formula | C10H16FN5 |
| Molecular Weight | 225.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Fluoro-N,N-dimethyl-2-(piperazin-1-yl)pyrimidin-4-amine (CAS 675588-46-2) is a high-purity analytical reference standard with the molecular formula C10H16FN5 and a molecular weight of 225.27 g/mol.
6-Fluoro-N,N-dimethyl-2-(piperazin-1-yl)pyrimidin-4-amine (C10H16FN5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Fluoro-N,N-dimethyl-2-(piperazin-1-yl)pyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H16FN5 |
| Molecular Weight | 225.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
- 4-Amino-3-(m-tolyl)-2,3-dihydro-1,2,5-thiadiazole 1,1-dioxide (CAS 425646-68-0)
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- 4-[2-(cyanomethyl)-1,3-thiazol-4-yl]benzonitrile (CAS 528522-91-0)
- 7-Hydroxy-2-isobutyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one (CAS 312316-18-0)
- 2-[4-(Bromomethyl)phenyl]-1,3-benzothiazole (CAS 24239-18-7)
- 6-((4-Nitrobenzyl)thio)-5H-purin-2-amine (CAS 5069-64-7)
- 4-fluoro-3-methanesulfonylphenol (CAS 2060020-74-6)
- 5-(1-(Dimethylamino)-1H-pyrrol-2-yl)pyridazine-4-carbonitrile (CAS 919785-71-0)
- 6,8-Dichloro-N-(3-fluoropyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamide (CAS 1177415-97-2)
- 1-(1-((4-Bromophenyl)sulfonyl)piperidin-4-yl)-3-(4-chlorophenyl)urea (CAS 672950-42-4)
- 2-Bromo-N-(6-methyl-pyridin-2-yl)-acetamide (CAS 349121-05-7)
- 1,3-Dibenzyloxy-2-propanol-d5 1189877-19-7 (CAS 1189877-19-7)
- n-(3-Methoxypropyl)quinoxalin-2-amine (CAS 1211081-93-4)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
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