2-(2-Bromo-4-chlorophenyl)acetonitrile CAS 52864-54-7
| CAS No. | 52864-54-7 |
| Molecular Formula | C8H5BrClN |
| Molecular Weight | 230.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2-Bromo-4-chlorophenyl)acetonitrile (CAS 52864-54-7) is a high-purity analytical reference standard with the molecular formula C8H5BrClN and a molecular weight of 230.49 g/mol.
The molecular framework of 2-(2-Bromo-4-chlorophenyl)acetonitrile (C8H5BrClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(2-Bromo-4-chlorophenyl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClN |
| Molecular Weight | 230.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-(3-Bromo-5-chlorophenyl)acetonitrile (CAS 1056454-88-6)
- 2-(5-Bromo-2-chlorophenyl)acetonitrile (CAS 1057216-52-0)
- 3-Bromo-6-chloro-1H-indole (CAS 1094641-40-3)
- 3-Bromo-4-chloro-1H-indole (CAS 1181332-74-0)
- 4-Bromo-5-chloro-1H-indole (CAS 1191028-48-4)
- 6-Bromo-5-chloro-1H-indole (CAS 1191028-50-8)
- 5-Bromo-6-chloroindole (CAS 122531-09-3)
- 4-Bromo-5-chloro-2-methylbenzonitrile (CAS 1228376-18-8)
Recommended Standards
- 5-Bromo-7-chloroindole (CAS 180623-89-6)
- 2-(2-Bromo-6-chlorophenyl)acetonitrile (CAS 76574-39-5)
- 7-Bromo-2-chloro-1H-indole (CAS 1782043-07-5)
- 2-(3-Bromo-4-chlorophenyl)acetonitrile (CAS 249647-28-7)
- (3-Fluoro-benzyl)-(3-trifluoromethoxy-propyl)-amine (CAS 1208079-71-3)
- tert-Butyl N-(trans-3-hydroxycyclobutyl)-N-methylcarbamate (CAS 1033718-20-5)
- 5-Cyclohexyl-1,2,4-oxadiazole-3-carboxylic acid (CAS 1342121-01-0)
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- (4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(1-ethyl-1H-pyrazol-5-yl)methanone (CAS 1172471-75-8)
- 6-Iodo-1H,2H,3H,4H-pyrrolo[2,1-f][1,2,4]triazine-2,4-dione (CAS 1313738-99-6)
- Ethyl 3-bromo-4-((4-fluorobenzyl)oxy)benzoate (CAS 1706456-47-4)
- Neuropeptide Y (2-36), amide, porcine (CAS 102961-52-4)
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