Ciprofloxacin 7-Chloro-6-Desethylene Impurity CAS 528851-30-1
| CAS No. | 528851-30-1 |
| Molecular Formula | C15H16ClN3O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 358.22 g/mol gives Ciprofloxacin 7-Chloro-6-Desethylene Impurity distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ciprofloxacin 7-Chloro-6-Desethylene Impurity (CAS 528851-30-1) is a certified pharmaceutical impurity reference standard with the molecular formula C15H16ClN3O3HCl and a molecular weight of 358.22 g/mol.
Ciprofloxacin 7-Chloro-6-Desethylene Impurity (C15H16ClN3O3HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ciprofloxacin 7-Chloro-6-Desethylene Impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H16ClN3O3 HCl |
| Molecular Weight | 358.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ciprofloxacin Standards
- Ciprofloxacin EP Impurity C (CAS 103222-12-4)
- Ciprofloxacin Impurity 14 (CAS 103237-52-1)
- Ciprofloxacin-acyl-Beta-D-glucuronide (CAS 105029-31-0)
- Ciprofloxacin impurity 43 (CAS 105093-21-8)
- Ciprofloxacin EP Impurity E (CAS 105394-83-0)
- Ciprofloxacin EP Impurity E（HCl） (CAS 105394-83-0(Free Base))
- Ciprofloxacin Ethyl Ester (CAS 105404-65-7)
- Ciprofloxacin Impurity 15 (CAS 105589-00-2)
Recommended Standards
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- 1-(2,4-Diethoxyphenyl)ethanol (CAS 1141669-81-9)
- N-(2-Aminoethyl)nicotinamide dihydrochloride (CAS 72627-93-1)
- 7-Iodo-5-((trifluoromethyl)thio)benzo[d]oxazole (CAS 1820736-27-3)
- 5-(2,5-Dioxopyrrolidin-1-yl) 2-methyl pyridine-2,5-dicarboxylate (CAS 1393590-58-3)
- 2,4-Diphenyl-5,6-dihydrobenzo[h]chromen-1-ium bromide (CAS 76192-30-8)
- Crustacean Cardioactive Peptide (CAS 107090-96-0)
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