1-Hydroxypyrrolidin-2-one CAS 52928-63-9
| CAS No. | 52928-63-9 |
| Molecular Formula | C4H7NO2 |
| Molecular Weight | 101.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 101.10 g/mol gives 1-Hydroxypyrrolidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-Hydroxypyrrolidin-2-one (CAS 52928-63-9) is a high-purity analytical reference standard with the molecular formula C4H7NO2 and a molecular weight of 101.10 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 1-Hydroxypyrrolidin-2-one is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 101.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Hydroxypyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H7NO2 |
| Molecular Weight | 101.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 1 |
Related Hydroxypyrrolidin Standards
- 3-Hydroxypyrrolidin-2-one (CAS 15116-68-4)
- (R)-3-Hydroxypyrrolidin-2-one (CAS 77510-50-0)
- (S)-3-Hydroxypyrrolidin-2-one (CAS 34368-52-0)
- (R)-2-(3-hydroxypyrrolidin-1-yl)acetonitrile (CAS 1260608-55-6)
- 2-(3-Hydroxypyrrolidin-3-yl)acetonitrile (CAS 1528010-57-2)
- 2-(4-Hydroxypyrrolidin-3-yl)acetonitrile (CAS 1780853-68-0)
- 2-(3-Hydroxypyrrolidin-1-yl)acetonitrile (CAS 857637-01-5)
- 1-Ethyl-3-hydroxypyrrolidin-2-one (CAS 614754-22-2)
Recommended Standards
- 1,2-Oxazinan-3-one (CAS 62079-06-5)
- 2-(Methoxymethoxy)acetonitrile (CAS 89426-76-6)
- (S)-Methyl aziridine-2-carboxylate (CAS 75154-69-7)
- 2-(Methylamino)acrylic acid (CAS 84888-65-3)
- 2-(Pyrimidin-2-yl)acetimidamide hydrochloride (CAS 2089315-75-1)
- 4-(4-amino-2,6-dimethylphenyl)morpholin-3-one (CAS 482308-12-3)
- 3-((1S,2S)-2-(trifluoromethyl)cyclopropyl)benzoic acid (CAS 1404192-15-9)
- 6-chloro-3-methyl-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 2138232-14-9)
- 5β-PREGNAN-3α, 17, 20β-TRIOL (CAS 1165-28-2)
- 1-((3-Phenyl-1,2,4-oxadiazol-5-yl)methyl)pyrrolidin-3-ol (CAS 1338680-18-4)
- 1-((4-Chlorophenyl)sulfonyl)-N'-(4-methylbenzoyl)piperidine-4-carbohydrazide (CAS 477872-85-8)
- Naftifine cis-Isomer (CAS 65473-08-7)
- 4-(Thiophen-2-yl)-1-((4-(trifluoromethyl)benzyl)sulfonyl)piperidine (CAS 1396768-65-2)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
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