3-Hydroxypyrrolidin-2-one CAS 15116-68-4
| CAS No. | 15116-68-4 |
| Molecular Formula | C4H7NO2 |
| Molecular Weight | 101.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 101.10 g/mol gives 3-Hydroxypyrrolidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Hydroxypyrrolidin-2-one (CAS 15116-68-4), a certified reference material (molecular formula C4H7NO2, MW 101.10 g/mol) for analytical method development and quality control.
The molecular framework of 3-Hydroxypyrrolidin-2-one (C4H7NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Hydroxypyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H7NO2 |
| Molecular Weight | 101.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Related Hydroxypyrrolidin Standards
- (R)-3-Hydroxypyrrolidin-2-one (CAS 77510-50-0)
- 1-Hydroxypyrrolidin-2-one (CAS 52928-63-9)
- (S)-3-Hydroxypyrrolidin-2-one (CAS 34368-52-0)
- (R)-2-(3-hydroxypyrrolidin-1-yl)acetonitrile (CAS 1260608-55-6)
- 2-(3-Hydroxypyrrolidin-3-yl)acetonitrile (CAS 1528010-57-2)
- 2-(4-Hydroxypyrrolidin-3-yl)acetonitrile (CAS 1780853-68-0)
- 2-(3-Hydroxypyrrolidin-1-yl)acetonitrile (CAS 857637-01-5)
- 1-Ethyl-3-hydroxypyrrolidin-2-one (CAS 614754-22-2)
Recommended Standards
- 1-hydroxycyclopropane-1-carboxamide (CAS 137682-88-3)
- Methyl vinylcarbamate (CAS 15204-93-0)
- (3S,4S)-3-amino-4-methyloxetan-2-one (CAS 131232-74-1)
- (4S)-4-aminooxolan-2-one (CAS 152580-30-8)
- N-(5-Oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)propane-1-sulfonamide (CAS 922009-09-4)
- 1-Methyl-3-(2-methylpropyl)-5-nitro-1H-pyrazole (CAS 956501-75-0)
- Lomefloxacin-d5 Hydrochloride (CAS CATO-CCAD301427)
- 5-Oxa-2-azaspiro[3.4]octane Hydrochloride (CAS 1359656-11-3)
- 2-(3-Chloro-2-nitrophenyl)acetonitrile (CAS 77158-79-3)
- 4-(Furan-2-yl)-2,6-dimethylnicotinonitrile (CAS 650605-90-6)
- 4-(4-Nitro-1H-pyrazol-1-yl)pyrimidin-2-amine (CAS 1260883-58-6)
- CAS 2206360-84-9 (CAS 2206360-84-9)
- 2-(4-Fluorophenyl)pyridine (CAS 58861-53-3)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
Why CATO?
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