Sorafenib Impurity 51 CAS 52943-20-1
| CAS No. | 52943-20-1 |
| Molecular Formula | C7H7ClN2O |
| Molecular Weight | 170.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Sorafenib Impurity 51 (C7H7ClN2O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Sorafenib Impurity 51 (CAS 52943-20-1), a pharmacopoeial impurity reference standard (molecular formula C7H7ClN2O, MW 170.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sorafenib Impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7ClN2O |
| Molecular Weight | 170.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Sorafenib Standards
- Sorafenib Impurity 67 (CAS 131418-11-6)
- Sorafenib Impurity 14 (CAS 845306-04-9)
- Sorafenib Impurity 47 (CAS 220000-87-3)
- Sorafenib Impurity 46 (CAS 53750-66-6)
- Sorafenib Impurity 50 (CAS 1065074-98-7)
- Sorafenib Impurity 54 (CAS 67455-41-8)
- Sorafenib Impurity 48 (CAS 5470-22-4)
- Sorafenib Impurity 64 (CAS 99586-65-9)
Recommended Standards
- 1-(4-Chlorophenyl)Urea (CAS 140-38-5)
- 1-Chloro-4-fluoro-2,3-dihydro-1h-indene (CAS 1082399-60-7)
- 2-Chloro-N-methylisonicotinamide (CAS CATO-C4X-104768)
- Tetrahydrofuran-3-sulfonyl Chloride (CAS 1207346-29-9)
- Ceftaroline Impurity 11 (CAS 953037-71-3)
- Etelcalcetide Impurity 22 X TFA Salt (CAS CATO-C4X-324722)
- Omeprazole Impurity 30 (CAS 727375-13-5)
- 1-Hexyl-3,4-dihydroxypyrrolidine-2,5-dione (CAS 446833-95-0)
- Imidazo[1,2-a]pyrazin-3-yl(phenyl)methanone (CAS 90734-76-2)
- tert-Butyl bis(4-hydroxybutyl)carbamate (CAS 1056441-60-1)
- Tert-butyl 2-((2-aminophenyl)sulfonyl)acetate (CAS 1326863-40-4)
- N-(4-Aminocyclohexyl)acrylamide hydrochloride (CAS 2446668-80-8)
- 4-Hydroxy-8-(propan-2-yl)quinoline-3-carboxylic acid (CAS 63136-17-4)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com