Cortisone CAS 53-06-5

Purity >95%In StockPharmaceutical Standards
CAS No.53-06-5
Molecular FormulaC21H28O5
Molecular Weight360.44 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Cortisone CAS 53-06-5 chemical structure

Description

Owing to a flavonoid core, a hydroxyl group, an ether linkage, Cortisone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 360.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Cortisone (CAS 53-06-5) is a high-purity analytical reference standard with the molecular formula C21H28O5 and a molecular weight of 360.44 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H28O5
Molecular Weight360.44 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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