Mexiletine EP Impurity B CAS 53012-41-2
| CAS No. | 53012-41-2 |
| Molecular Formula | C11H14O2 |
| Molecular Weight | 178.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Mexiletine EP Impurity B (C11H14O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Mexiletine EP Impurity B (CAS 53012-41-2), a pharmacopoeial impurity reference standard (molecular formula C11H14O2, MW 178.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Mexiletine EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14O2 |
| Molecular Weight | 178.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
Related Mexiletine Standards
- Mexiletine Impurity N5 (CAS 117322-90-4)
- Mexiletine impurity N1 (CAS 117322-92-6)
- Mexiletine Impurity N3 (CAS 180966-61-4)
- Mexiletine EP Impurity D(Enantiomer Mixture) (CAS 26583-71-1)
- Mexiletine Alcohol (CAS 61102-09-8)
- Mexiletine Impurity 17 (CAS CATO-C4X-192917)
- Mexiletine Impurity 11 (CAS 284486-96-0)
- Mexiletine Impurity N4 (CAS 1051392-53-0)
Recommended Standards
- Nikethamide Impurity 8 (CAS 530-40-5)
- rac-Nicotine EP Impurity E (CAS 63551-14-4)
- Nikethamide Impurity 1 (CAS 7606-13-5)
- Sivelestat Impurity 26 (CAS 4920-92-7)
- Temozolomide Impurity 19 (CAS CATO-C4X-135319)
- Vildagliptin Impurity 26 (CAS CATO-C4X-110026)
- Hydrocortisone EP Impurity J (CAS 16463-74-4)
- N-(3-methoxybenzyl)cyclopropanamine hydrochloride (CAS 1050419-13-0)
- 09T3687932 4755-81-1 Methyl 2-chloroacetoacetate Butanoic acid, 2-chloro-3-oxo-, methyl ester EINECS 225-286-6 UNII-09T3687932 (CAS 4755-81-1)
- 4-Cyclopropyl-2-methylbenzoic acid (CAS 909698-10-8)
- 1-[2-(Difluoromethoxy)phenyl]ethanone (CAS 127842-55-1)
- H-Lys(Tfa)-OH (CAS 10009-20-8)
- Methyl 2-hydroxy-4-methyl-2-(trifluoromethyl)pent-4-enoate (CAS 117015-42-6)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com