O763YB84E3 53174-06-4 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (-)- UNII-O763YB84E3 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2S)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (S)- (-)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (S)-(-)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (S)-(-)-Trolox (S)-Trolox CAS 53174-06-4
| CAS No. | 53174-06-4 |
| Molecular Formula | C14H24O4 |
| Molecular Weight | 256.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of O763YB84E3 53174-06-4 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (-)- UNII-O763YB84E3 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2S)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (S)- (-)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (S)-(-)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (S)-(-)-Trolox (S)-Trolox is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
O763YB84E3 53174-06-4 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (-)- UNII-O763YB84E3 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2S)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (S)- (-)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (S)-(-)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (S)-(-)-Trolox (S)-Trolox (CAS 53174-06-4), molecular formula C14H24O4 and molecular weight 256.34 g/mol, is a CATO reference standard with documented purity and traceability.
O763YB84E3 53174-06-4 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (-)- UNII-O763YB84E3 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2S)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (S)- (-)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (S)-(-)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (S)-(-)-Trolox (S)-Trolox (C14H24O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H24O4 |
| Molecular Weight | 256.34 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
Recommended Standards
- 1O8B70QB9P 53101-49-8 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (+)- UNII-1O8B70QB9P 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2R)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (R)- (+)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (R)-Trolox (CAS 53101-49-8)
- 773087-36-8 A839030 N-[3-(1,3-dioxolan-2-yl)-4-pyridinyl]-2,2-dimethylpropanamide N-[3-(1,3-dioxolan-2-yl)pyridin-4-yl]-2,2-dimethyl-propanamide (CAS 773087-36-8)
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