Mefloquine CAS 53230-10-7
| CAS No. | 53230-10-7 |
| Molecular Formula | C17H16F6N2O |
| Molecular Weight | 378.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Mefloquine (CAS 53230-10-7), molecular formula C17H16F6N2O and molecular weight 378.31 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C17H16F6N2O, Mefloquine contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 378.31 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H16F6N2O |
| Molecular Weight | 378.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Mefloquine Standards
Recommended Standards
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- O,O-dimethyl O-{6-methyl-2-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl} phosphothioate (CAS 680216-32-4)
- N,N'-(cyclohexane-1,2-diyl)bis(1,1,1-trifluoromethanesulfonamide) (CAS 153077-87-3)
- (E)-4-(3-Bromophenyl)-1-(4-bromophenyl)but-3-en-1-one (CAS 1321685-46-4)
- 1,2,3,4,5,6-Hexakis[2-(methyldichlorosilyl)ethyl]benzene (CAS 194933-15-8)
- 3-Chloro-N-(4-(trifluoromethoxy)phenyl)naphtho[1,2-b]thiophene-2-carboxamide (CAS 1024164-16-6)
- N-Succinyl-5-aminoimidazole-4-carboxamide Ribose 2,3,5-Triacetate (CAS 17388-80-6)
- 3-Chloro-2-(3,3-difluorocyclobutyl)pyridine (CAS 1355070-38-0)
- 6-methyl-5H,10H-benzo[b]1,6-naphthyridin-10-one (CAS 157610-19-0)
- Boc-(2S,4R)-4-hydroxypiperidine-2-carboxylic acid (CAS 917835-93-9)
- 2-(2H-Isoindol-2-yl)acetic 5-oxocyclohex-3-enecarboxylic anhydride (CAS 38068-73-4)
- trans-N-[4-(hydroxymethyl)cyclohexyl]ethanesulfonamide (CAS 2169920-32-3)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
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