2-hydroxy-5-(1H-imidazol-1-yl)benzoic acid CAS 53242-52-7
| CAS No. | 53242-52-7 |
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-hydroxy-5-(1H-imidazol-1-yl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-hydroxy-5-(1H-imidazol-1-yl)benzoic acid (CAS 53242-52-7), molecular formula C10H8N2O3 and molecular weight 204.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 2-hydroxy-5-(1H-imidazol-1-yl)benzoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 2 |
Related hydroxy Standards
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- 3-Hydroxy-4-phenyl-1H-pyrazole-5-carboxylic acid (CAS 1144488-84-5)
- 4-Hydroxy-6-methyl-2-oxo-2H-chromene-3-carbaldehyde (CAS 126214-23-1)
- 4-Hydroxy-6-methylquinazoline-8-carboxylic acid (CAS 1269421-64-8)
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Recommended Standards
- 2-HYdroxy-3-nitroquinoline oh-form, me ether (CAS 36255-31-9)
- 2-Hydroxy-6-methoxynaphthalene-1,4-dione (CAS 6223-31-0)
- 2-Ethyl-6-hydroxyquinoxaline-5,8-dione (CAS 61373-05-5)
- 2-Hydroxy-7-methoxynaphthalene-1,4-dione (CAS 6551-27-5)
- N,N,N-trimethyl-1-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanaminium iodide (CAS 106961-34-6)
- 3,4,5-Tribromo-1-methyl-pyrazole (CAS 57389-75-0)
- 2-Bromo-5-hydrazinylpyridine (CAS 1268882-60-5)
- 1-Benzyl-3-hydroxypiperidine-3-carboxylic acid hydrochloride (CAS 112197-87-2)
- tert-Butyl 5-formyl-1,2,3,4-tetrahydropyridine-1-carboxylate (CAS 1374654-03-1)
- N-((5-mercapto-4-methyl-4H-1,2,4-triazol-3-yl)methyl)-4-methylbenzenesulfonamide (CAS 338421-91-3)
- [1,3]Dioxolo[4,5-c]pyridin-4-ylmethanol (CAS 139645-23-1)
- 2-Ethyl-5-(1H-indol-2-yl)-1,3,4-thiadiazole (CAS 757213-72-2)
- Rivastigmine Impurity 15 (CAS 169772-44-5)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
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