2-(Isoquinolin-4-yl)acetic acid hydrochloride CAS 53366-30-6
| CAS No. | 53366-30-6 |
| Molecular Formula | C11H9NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(Isoquinolin-4-yl)acetic acid hydrochloride (CAS 53366-30-6), a certified reference material (molecular formula C11H9NO2HCl, MW 223.66 g/mol) for analytical method development and quality control.
2-(Isoquinolin-4-yl)acetic acid hydrochloride (C11H9NO2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9NO2 HCl |
| Molecular Weight | 223.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Isoquinolin Standards
- 2-(Isoquinolin-6-yl)ethanamine (CAS 1000505-67-8)
- 2-(Isoquinolin-8-yl)acetic acid (CAS 1000517-56-5)
- 2-(Isoquinolin-5-yl)ethan-1-ol (CAS 1000521-95-8)
- 2-(Isoquinolin-8-yl)acetonitrile (CAS 1000527-77-4)
- 2-(Isoquinolin-8-yl)ethan-1-amine (CAS 1000538-18-0)
- 3-(Isoquinolin-5-yl)propan-1-ol (CAS 1000542-34-6)
- 2-(Isoquinolin-6-yl)acetic acid (CAS 1000545-64-1)
- Isoquinolin-5-ylmethanamine hydrochloride (CAS 1001906-56-4)
Recommended Standards
- 4’-Ethyl-2-hydroxyacetophenone (CAS 103323-24-6)
- 3-((2-Fluorobenzyl)thio)-5-(p-tolyl)-4h-1,2,4-triazol-4-amine (CAS 676582-23-3)
- 2-(2-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-7-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine (CAS 478258-90-1)
- Ethyl 5-bromo-1,2,3-thiadiazole-4-carboxylate (CAS 6439-91-4)
- 3-Acetyl-N-benzyloxycarbonyl-L-tyrosine Methyl Ester (CAS 110774-03-3)
- 3-(Furan-2-yl)pyrazine-2-carbaldehyde (CAS 1823498-75-4)
- 2-amino-4,5-dimethoxymethylesterbenzoic acid (CAS 26759-46-6)
- 4-(Benzylamino)-N-(1-ethylpyrrolidin-2-ylidene)benzenesulfonamide (CAS 126826-53-7)
- 3,5-Dibromo-4-chloropicolinic acid (CAS 698393-07-6)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
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