Methadone Hydrochloride - Impurity D (Hydrochloride Salt) CAS 5341-49-1
| CAS No. | 5341-49-1 |
| Molecular Formula | C21H27NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Methadone Hydrochloride - Impurity D (Hydrochloride Salt) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 345.91 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Methadone Hydrochloride - Impurity D (Hydrochloride Salt) (CAS 5341-49-1), a certified reference material (molecular formula C21H27NOHCl, MW 345.91 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H27NO HCl |
| Molecular Weight | 345.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methadone Standards
- Methadone Hydrochloride (CAS 1095-90-5)
- Methadone Impurity 6 (CAS 117449-78-2)
- Methadone Impurity A (CAS 14474-54-5)
- (S)-Methadone hydrochloride (CAS 15284-15-8)
- (R)-Methadone hydrochloride (CAS 5967-73-7)
- (±)-Methadone-D3 (CAS 60263-63-0)
- Methadone Impurity C (CAS 6293-01-2)
- rac Methadone-d3 Hydrochloride (100ug/mL in Methanol) (CAS 65566-72-5)
Recommended Standards
- 2-(5-Bromo-2-fluorophenyl)acetonitrile, 97% (CAS 305800-60-6)
- N-(4-Chlorophenyl)-2,5-dimethylbenzenesulfonamide (CAS 71796-20-8)
- (1-Cyclopropylvinyl)benzene (CAS 825-76-3)
- n-((5-Bromothiophen-2-yl)methyl)cycloheptanamine (CAS 1038278-40-8)
- 2-Fluoro-1-nitro-3-propoxybenzene (CAS 1881321-08-9)
- Boc-NH-PEG11-CH2CH2N3 (CAS 2395004-21-2)
- 2-Ethyl-2-(4-methyl-piperidin-1-ylmethyl)-hexanal (CAS 865074-67-5)
- 2-(Aminomethyl)-3-bromo-6-cyano-4-(difluoromethyl)pyridine (CAS 1806842-27-2)
- (Z)-4,4'-(Ethene-1,2-diyl)dibenzoic acid (CAS 133005-88-6)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com