3-Hydroxynaphthalene-2-carbohydrazide CAS 5341-58-2
| CAS No. | 5341-58-2 |
| Molecular Formula | C11H10N2O2 |
| Molecular Weight | 202.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Hydroxynaphthalene-2-carbohydrazide.
3-Hydroxynaphthalene-2-carbohydrazide (CAS 5341-58-2) is a high-purity analytical reference standard with the molecular formula C11H10N2O2 and a molecular weight of 202.21 g/mol.
3-Hydroxynaphthalene-2-carbohydrazide (C11H10N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10N2O2 |
| Molecular Weight | 202.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Hydroxynaphthalene Standards
- 1-Hydroxynaphthalene-2-carbohydrazide (CAS 7732-44-7)
- 2-Ethyl-3-hydroxynaphthalene-1,4-dione (CAS 29366-44-7)
- 4-Hydroxynaphthalene-1,3-dicarbaldehyde (CAS 933775-00-9)
- 3-hydroxynaphthalene-1-carboxylic acid (CAS 19700-42-6)
- 5-hydroxynaphthalene-1-carboxylic acid (CAS 2437-16-3)
- 7-hydroxynaphthalene-1-carboxylic acid (CAS 2623-37-2)
- 7-hydroxynaphthalene-2-carboxylic acid (CAS 613-17-2)
- 8-hydroxynaphthalene-2-carboxylic acid (CAS 5776-28-3)
Recommended Standards
- 3-Cyclopropylquinazoline-2,4(1H,3H)-dione (CAS 30385-94-5)
- 3-Methoxy-2-naphthoic acid (CAS 883-62-5)
- 3-Cyclopropylimidazo[1,5-a]pyridine-1-carboxylic acid (CAS 924646-07-1)
- 3-Methoxy-4-(1H-pyrazol-1-yl)benzaldehyde (CAS 433920-87-7)
- CAY10509 (CAS 1245699-47-1)
- 3-(3-Bromo-4,5-dimethoxyphenyl)acrylic acid (CAS 51314-72-8)
- 3937AE 457098-40-7 C12H20N2O N-[3-(2-Amino-4-methylphenoxy)propyl]-N,N-dimethylamine (CAS 457098-40-7)
- (2,2-Dimethylcyclopentyl)methanamine (CAS 212382-59-7)
- 5,7-Di-tert-butyl-3-(2,3-dimethylphenyl)benzofuran-2(3H)-one (CAS 169198-26-9)
- 1-(3,5-Dichloropyridin-2-yl)propan-2-one (CAS 1487892-44-3)
- (3-Bromo-5-chloropyridin-4-yl)methanol (CAS 1064677-18-4)
- Ethyl (1S,3S,4R)-2-((S)-1-phenylethyl)-2-azabicyclo[2.2.1]Heptane-3-carboxylate (CAS 192461-70-4)
- 7-Methoxybenzo[d]oxazol-2-amine (CAS 1554147-50-0)
- (Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) (CAS 161650-01-7)
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