Pirfenidone Impurity 36 CAS 53427-80-8
| CAS No. | 53427-80-8 |
| Molecular Formula | C12H10ClNO |
| Molecular Weight | 219.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Pirfenidone Impurity 36 (CAS 53427-80-8) is a certified pharmaceutical impurity reference standard with the molecular formula C12H10ClNO and a molecular weight of 219.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Pirfenidone Impurity 36 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 219.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Pirfenidone Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO |
| Molecular Weight | 219.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pirfenidone Standards
- Pirfenidone Impurity 37 (CAS CATO-C4X-222937)
- Pirfenidone Impurity 22 (CAS CATO-C4X-222922)
- Pirfenidone Impurity 34 (CAS 77837-08-2)
- Pirfenidone Impurity 48 (CAS CATO-C4X-222948)
- Pirfenidone Impurity 10 (CAS CATO-C4X-222910)
- Pirfenidone Impurity 12 (CAS 887406-49-7)
- Pirfenidone Impurity 21 (CAS 887406-53-3)
- Pirfenidone Impurity 23 (CAS 851518-71-3)
Recommended Standards
- Betahistine Impurity 21 (CAS 6238-67-1)
- 97090-93-2 1-(4-Chlorophenyl)-2-(1H-pyrrol-1-yl)ethanone MFCD14281582 (CAS 97090-93-2)
- (4-Chlorophenyl)(pyridin-2-yl)methanol (CAS 27652-89-7)
- 6628-13-3 Benzenamine,4-chloro-2-phenoxy- CTK5C3994 (CAS 6628-13-3)
- Benzonatate Impurity 3 (CAS CATO-C4X-30663)
- Medroxyprogesterone Impurity 14 (CAS CATO-C4X-145714)
- Iopamidol EP Impurity H (CAS CATO-C4X-145011)
- Ethyl (1-(2-hydroxyethyl)-3-phenyl-1H-pyrazol-5-yl)carbamate (CAS 1226439-09-3)
- 5-Methyl-N-(4-(2-(pyridin-3-ylamino)thiazol-4-yl)phenyl)thiophene-2-sulfonamide (CAS 1797641-49-6)
- 3-(2-(tert-Butoxycarbonyl)isoindolin-4-yl)propanoic acid (CAS 2633650-38-9)
- Ceftibuten Impurity 15 (CAS CATO-C4X-189015)
- N1-(4-Fluorophenyl)-N2-(2-methoxyethyl)oxalamide (CAS 352013-10-6)
- 2-(Methoxycarbonyl)benzofuran-5-carboxylic acid (CAS 166952-92-7)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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