Betahistine Impurity 21 CAS 6238-67-1
| CAS No. | 6238-67-1 |
| Molecular Formula | C12H10ClNO |
| Molecular Weight | 219.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Betahistine Impurity 21 (CAS 6238-67-1), a pharmacopoeial impurity reference standard (molecular formula C12H10ClNO, MW 219.67 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Betahistine Impurity 21 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 219.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Betahistine Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO |
| Molecular Weight | 219.67 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Betahistine Standards
- Betahistine impurity 31 (CAS 91029-17-3)
- Betahistine Impurity 45 (CAS 128225-22-9)
- Betahistine EP Impurity C (CAS 5452-87-9)
- Betahistine impurity 34 (CAS 37445-98-0)
- Betahistine Impurity 24 (CAS CATO-C4X-183824)
- Betahistine impurity 29 (CAS CATO-C4X-183829)
- Betahistine impurity 30 (CAS CATO-C4X-183830)
- Betahistine Impurity 46 (CAS 1903526-05-5)
Recommended Standards
- 97090-93-2 1-(4-Chlorophenyl)-2-(1H-pyrrol-1-yl)ethanone MFCD14281582 (CAS 97090-93-2)
- Pirfenidone Impurity 36 (CAS 53427-80-8)
- 6628-13-3 Benzenamine,4-chloro-2-phenoxy- CTK5C3994 (CAS 6628-13-3)
- Pirfenidone Impurity 37 (CAS CATO-C4X-222937)
- Nabumetone Impurity 17 (CAS CATO-C4X-284817)
- Minoxidil Impurity 41 (CAS CATO-C4X-170041)
- Melitracen Impurity 18 (CAS CATO-C4X-120218)
- 3'-Amino-[1,1'-biphenyl]-2-carbonitrile (CAS 342613-84-7)
- 5-Cyclopropoxy-2-isopropyl-4-(methylthio)pyridine (CAS 1243353-12-9)
- Miriplatin (CAS 141977-79-9)
- N-(4-(((1-Benzyl-2,2-dioxido-4-oxo-1,4-dihydro-3H-benzo[c][1,2]thiazin-3-ylidene)methyl)amino)phenyl)acetamide (CAS 893315-82-7)
- Pinaverium Impurity 37 (CAS 266689-70-7)
- Methyl 2-formyl-6-methoxyisonicotinate (CAS 1393533-87-3)
- Semaglutide impurity 70 (CAS CATO-C4X-222670)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com