1-Methyl-5-trifluoromethylbenzimidazole CAS 53483-66-2
| CAS No. | 53483-66-2 |
| Molecular Formula | C9H7F3N2 |
| Molecular Weight | 200.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Methyl-5-trifluoromethylbenzimidazole.
CATO supplies 1-Methyl-5-trifluoromethylbenzimidazole (CAS 53483-66-2), a certified reference material (molecular formula C9H7F3N2, MW 200.16 g/mol) for analytical method development and quality control.
Based on its molecular formula C9H7F3N2, 1-Methyl-5-trifluoromethylbenzimidazole contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 200.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7F3N2 |
| Molecular Weight | 200.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 1-Methyl-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 384-46-3)
- 2-(1-Amino-2,2,2-trifluoroethyl)benzonitrile (CAS 886368-74-7)
- 1-Methoxy-4-(trifluoroprop-1-yn-1-yl)benzene (CAS 82203-83-6)
- 2-(2,2-Difluorocyclopropyl)-3-fluorobenzaldehyde (CAS 2755372-45-1)
- 4-(N,N-Dimethylsulfamoyl)phenylboronic Acid (CAS 486422-59-7)
- 8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one (CAS 147568-66-9)
- 3,4,5-Trimethoxy-N-(1-(3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)benzamide (CAS 1396635-04-3)
- 4-Hydrazinyl-7-(trifluoromethyl)quinoline hydrochloride (CAS 88164-54-9)
- 4-Amino-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS 77289-98-6)
- 4-[(4-Methoxyphenyl)sulfanyl]-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 338420-32-9)
- 1174044-75-7 4-(Tetrahydro-2-furanylmethoxy)piperidine hydrochloride 9955AC C10H20ClNO2 (CAS 1174044-75-7)
- 1-(2,2-Difluoro-2-phenylethyl)piperazine (CAS 189298-26-8)
- 6-[(E)-2-(4-Methylphenyl)ethenyl]-4-[(Z)-2-(4-methylphenyl)ethenyl]-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyridine-3-carbonitrile (CAS 303985-30-0)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com