Cefaclor Impurity 40 HCI CAS 53483-70-8
| CAS No. | 53483-70-8 |
| Molecular Formula | C14H12ClN3O5S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 406.23 g/mol gives Cefaclor Impurity 40 HCI distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Cefaclor Impurity 40 HCI (CAS 53483-70-8, C14H12ClN3O5SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefaclor Impurity 40 HCI (C14H12ClN3O5SHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Cefaclor Impurity 40 HCI under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12ClN3O5S HCl |
| Molecular Weight | 406.23 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cefaclor Standards
- Cefaclor Impurity C10 (CAS 108260-07-7)
- Cefaclor Impurity 46 (CAS 134624-91-2&6453-64-1 (mixture))
- Cefaclor Impurity 23 (CAS 1426173-90-1)
- Cefaclor Impurity 24 (CAS 142975-51-7)
- Cefaclor EP Impurity C (CAS 143059-69-2)
- Cefaclor EP Impurity D (Mixture of Diastereomers) (CAS 152575-13-8)
- Cefaclor EP Impurity E (CAS 188915-50-6)
- Cefaclor Impurity 37 (CAS 21746-02-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com