m-Tolylmethanesulfonyl chloride CAS 53531-68-3
| CAS No. | 53531-68-3 |
| Molecular Formula | C8H9ClO2S |
| Molecular Weight | 204.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of m-Tolylmethanesulfonyl chloride (C8H9ClO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
m-Tolylmethanesulfonyl chloride (CAS 53531-68-3), molecular formula C8H9ClO2S and molecular weight 204.67 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures m-Tolylmethanesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9ClO2S |
| Molecular Weight | 204.67 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Recommended Standards
- methyl 4-(chloromethyl)-5-methylthiophene-2-carboxylate (CAS 28686-93-3)
- o-Tolyl-methanesulfonyl chloride o-tolyl methanesulfonyl chloride 2-methylbenzylsulphonyl chloride ((2-methylphenyl)methyl)sulfonyl chloride (2-methylphenyl)methanesulfonyl chloride 92614-55-6 (CAS 92614-55-6)
- Ethyl 5-chloro-4-methylthiophene-2-carboxylate (CAS 74598-04-2)
- Vortioxetine Impurity 29 (CAS 609-60-9)
- Benzyl (R)-(4-aminobutan-2-yl)carbamate hydrochloride (CAS 1414960-65-8)
- N'-(4,6-Difluorobenzo[d]thiazol-2-yl)-3-fluorobenzohydrazide (CAS 851988-19-7)
- 5-Nitro-2-(pyridin-4-yl)-1H-benzo[d]imidazole (CAS 148533-73-7)
- (6-Hydroxy-4-methylpyridin-3-yl)boronic acid (CAS 1598436-72-6)
- Bufexamac (CAS 2438-72-4)
- Bisoprolol Impurity 122 (CAS CATO-C4X-1247122)
- 4-Bromo-3-iodo-1H-indazole-6-carboxylic acid (CAS 885523-54-6)
- 2-(Adamantan-1-ylamino)-2-oxoethyl picolinate (CAS 380486-73-7)
- 4-Methanesulfonylcyclohexane-1-carboxylic acid (CAS 1557624-71-1)
- [β-Asp]9-Semaglutide (CAS CATO-CPTD788605)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com