methyl 4-(chloromethyl)-5-methylthiophene-2-carboxylate CAS 28686-93-3
| CAS No. | 28686-93-3 |
| Molecular Formula | C8H9ClO2S |
| Molecular Weight | 204.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies methyl 4-(chloromethyl)-5-methylthiophene-2-carboxylate (CAS 28686-93-3), a certified reference material (molecular formula C8H9ClO2S, MW 204.67 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, methyl 4-(chloromethyl)-5-methylthiophene-2-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), methyl 4-(chloromethyl)-5-methylthiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9ClO2S |
| Molecular Weight | 204.67 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related methyl Standards
- 4-(Chloromethyl)-2-(thiophen-3-yl)-1,3-dioxolane (CAS 1556649-68-3)
- 1-(Chloromethyl)-2-methanesulfonylbenzene (CAS 168551-51-7)
- Ethyl 3-(chloromethyl)thiophene-2-carboxylate (CAS 1823887-17-7)
- 1-((Chloromethyl)sulfonyl)-4-methylbenzene (CAS 7569-26-8)
- 1-Chloromethyl-3-methanesulfonylbenzene (CAS 586373-70-8)
- 4-(chloromethyl)-2-(thiophen-2-yl)-1,3-dioxolane (CAS 93676-36-9)
- 6-(Chloromethyl)-2,3'-bipyridine (CAS 1227508-91-9)
- 4-(Chloromethyl)-2,3'-bipyridine (CAS 1227586-43-7)
Recommended Standards
- Ethyl 5-chloro-4-methylthiophene-2-carboxylate (CAS 74598-04-2)
- m-Tolylmethanesulfonyl chloride (CAS 53531-68-3)
- 4-Chlorobenzyl methyl sulfone (CAS 5925-80-4)
- o-Tolyl-methanesulfonyl chloride o-tolyl methanesulfonyl chloride 2-methylbenzylsulphonyl chloride ((2-methylphenyl)methyl)sulfonyl chloride (2-methylphenyl)methanesulfonyl chloride 92614-55-6 (CAS 92614-55-6)
- Lactose Heptasulfate (CAS CATO-C3D-262596)
- 5-Hydroxy-Clethodim Sulfone (CAS 111031-11-9)
- (6-Chloropyridazin-3-yl)glycine (CAS 17284-99-0)
- 1-(2-Bromophenyl)-3-oxocyclobutanecarbonitrile (CAS 1341872-18-1)
- 1-Amino-3-(1-phenylpropoxy)propan-2-ol (CAS 524730-43-6)
- cyclohexyloxy-cyclohexane (CAS 4645-15-2)
- 3-(Tert-butyl)-2h-pyrazolo[3,4-b]pyridin-5-amine (CAS 1368167-04-7)
- 2-Oxo-1-oxaspiro[4.5]Decane-4-carboxylic acid (CAS 2819-56-9)
- Ethyl 5-cyano-6-{[(2,4-dichlorophenyl)methyl]amino}-2-phenylpyridine-3-carboxylate (CAS 477866-13-0)
- MLCK inhibitor peptide 18 (CAS 224579-74-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com