2-Amino-1-(1H-indol-3-yl)ethanone hydrochloride CAS 53552-11-7
| CAS No. | 53552-11-7 |
| Molecular Formula | C10H10N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Amino-1-(1H-indol-3-yl)ethanone hydrochloride (CAS 53552-11-7), molecular formula C10H10N2OHCl and molecular weight 210.66 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-1-(1H-indol-3-yl)ethanone hydrochloride (C10H10N2OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Amino-1-(1H-indol-3-yl)ethanone hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O HCl |
| Molecular Weight | 210.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 3-(2-Oxobenzo[d]oxazol-3(2H)-yl)-N-(thiophen-2-ylmethyl)propanamide (CAS 851988-93-7)
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- 3-(Difluoromethyl)cyclohexan-1-one (CAS 1355729-67-7)
- Penicillin V (CAS 87-08-1)
- 3-(Trichloromethyl)pyridine (CAS 3099-50-1)
- 2-Chloro-7-fluoroquinazoline-4-acetic Acid (CAS 1784613-73-5)
- (R)-2-(4-((Benzyloxy)carbonyl)piperazin-2-yl)acetic acid (CAS 1932109-07-3)
- 4-(4-Methyl-1,1-dioxido-3-oxoisothiazolidin-2-yl)benzoyl chloride (CAS 927999-08-4)
- Cyclohexyl(2,7-diazaspiro[3.5]nonan-2-yl)methanone (CAS 1782522-59-1)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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