6-Iodopyrimidin-4-amine CAS 53557-69-0
| CAS No. | 53557-69-0 |
| Molecular Formula | C4H4IN3 |
| Molecular Weight | 221.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-Iodopyrimidin-4-amine (CAS 53557-69-0), a certified reference material (molecular formula C4H4IN3, MW 221.00 g/mol) for analytical method development and quality control.
The molecular framework of 6-Iodopyrimidin-4-amine (C4H4IN3) is characterized by a nitrile group, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H4IN3 |
| Molecular Weight | 221.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iodopyrimidin Standards
- 2-Iodopyrimidin-5-amine (CAS 1378847-85-8)
- 2-Iodopyrimidin-4-amine (CAS 1807180-37-5)
- 4-Iodopyrimidin-5-amine (CAS 942067-98-3)
- 5-iodopyrimidin-4-amine (CAS 91416-96-5)
- 4-Iodopyrimidin-5-ol (CAS 161286-33-5)
- 5-Iodopyrimidin-2(1H)-one (CAS 79387-69-2)
- 5-Iodopyrimidin-4-ol (CAS 4349-07-9)
- (2-Iodopyrimidin-4-yl)methanol (CAS 2280988-98-7)
Recommended Standards
- 6-Iodopyridazin-4-amine (CAS 2408968-66-9)
- heptyl carbamate (CAS 4248-20-8)
- 6-Chloro-5-nitronicotinoyl chloride (CAS 23945-84-8)
- 3-Fluorophthaloyl dichloride (CAS 113770-86-8)
- 9-(2,6-Dimethoxyphenyl)-1,8-dimethoxy-9H-xanthen-9-ol (CAS 95431-58-6)
- 1-(4-(Benzyloxy)phenyl)-3-phenylthiourea (CAS 335218-44-5)
- 5-Ethyl-N-(1-(furan-2-carbonyl)indolin-6-yl)thiophene-2-sulfonamide (CAS 1040661-56-0)
- 4-(4-ethoxy-3-fluorophenyl)-4-oxobutanoic acid (CAS 1797723-62-6)
- 1,1-Bis((2R,5R)-2,6-dimethylphospholano)ferrocene(cyclooctadiene)rhodium(I) tetrafluoroborate (CAS 854275-88-0)
- N-(2,4-difluorophenyl)-2-(N-phenylphenylsulfonamido)acetamide (CAS 339102-95-3)
- Ethyl 2-(4-(4-bromophenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetate (CAS 343373-40-0)
- 2-Cyano-N-(1-(p-tolyl)ethyl)acetamide (CAS 444907-79-3)
- 3,6-Dichloro-1H-pyrazolo[3,4-b]pyrazine (CAS 2387248-25-9)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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