Imidazo[2,1-b]thiazole-6-carboxylic Acid CAS 53572-98-8
| CAS No. | 53572-98-8 |
| Molecular Formula | C6H4N2O2S |
| Molecular Weight | 168.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Imidazo[2,1-b]thiazole-6-carboxylic Acid is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Imidazo[2,1-b]thiazole-6-carboxylic Acid (CAS 53572-98-8), molecular formula C6H4N2O2S and molecular weight 168.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Imidazo[2,1-b]thiazole-6-carboxylic Acid (C6H4N2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Imidazo[2,1-b]thiazole-6-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4N2O2S |
| Molecular Weight | 168.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Imidazo Standards
- Imidazo[4,3-b][1,3]thiazole-3-carboxylic acid (CAS 1306605-02-6)
- imidazo[2,1-b][1,3]thiazole-2-carboxylic acid (CAS 773841-78-4)
- imidazo[2,1-b][1,3]thiazole-3-carboxylic acid (CAS 479028-73-4)
- Imidazo[5,1-b]thiazole-7-carboxylic acid (CAS 211033-78-2)
- Imidazo[5,1-a]isoquinoline (CAS 234-61-7)
- 1-(imidazo[1,2-a]pyridin-7-yl)ethanone (CAS 1036991-50-0)
- 1-{imidazo[1,2-a]pyridin-6-yl}ethan-1-one (CAS 944905-12-8)
- Imidazo[2,1-b]thiazole-6-ethanamine (CAS 933698-24-9)
Recommended Standards
- Methyl 2-(methanesulfonyloxy)acetate (CAS 23550-26-7)
- Enzalutamide Impurity N4 (CAS 869936-86-7)
- N-(2-amino-4-fluorophenyl)acetamide (CAS 22380-13-8)
- Dimethyl(4-methylphenyl)phosphine oxide (CAS 53888-89-4)
- N-(2-Methoxyphenyl)-4-phenylthiazol-2-amine (CAS 3394-23-8)
- 2-(3-Ethyl-4-oxo-2-(phenylimino)thiazolidin-5-yl)acetic acid (CAS 104445-59-2)
- 2-(Cyclobutylamino)isonicotinic acid (CAS 1251225-65-6)
- 2-Aminopent-4-en-1-ol (CAS 304020-67-5)
- 8-Methyl-3,8-diazabicyclo[4.2.0]octane bis(trifluoroacetic acid) (CAS 2007924-92-5)
- 4-Imino-N,N-dimethyl-1,4-dihydropyrimidin-2-amine (CAS 1074-34-6)
- 3-Allyl-5-phenylaminomethylene-2-thioxo-thiazolidin-4-one (CAS 41523-26-6)
- 34415-10-6 4-Pyrimidinecarboxylic acid, 1,6-dihydro-2-methyl-6-oxo- (9CI) 4-Pyrimidinecarboxylic acid, 6-hydroxy-2-methyl- 2-Methylorotic acid NSC 58348 (CAS 34415-10-6)
- 2-[(4-Methylphenyl)sulfanyl]-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-1-ethanone (CAS 478047-41-5)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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