(2R)-1-tert-butoxycarbonyl-4,4-difluoro-pyrrolidine-2-carboxylic acid CAS 536747-87-2
| CAS No. | 536747-87-2 |
| Molecular Formula | C10H15F2NO4 |
| Molecular Weight | 251.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2R)-1-tert-butoxycarbonyl-4,4-difluoro-pyrrolidine-2-carboxylic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2R)-1-tert-butoxycarbonyl-4,4-difluoro-pyrrolidine-2-carboxylic acid (CAS 536747-87-2) is a high-purity analytical reference standard with the molecular formula C10H15F2NO4 and a molecular weight of 251.23 g/mol.
Based on its molecular formula C10H15F2NO4, (2R)-1-tert-butoxycarbonyl-4,4-difluoro-pyrrolidine-2-carboxylic acid contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 251.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2R)-1-tert-butoxycarbonyl-4,4-difluoro-pyrrolidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H15F2NO4 |
| Molecular Weight | 251.23 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-Ethoxy-5-fluoro-N-(4-fluorophenyl)pyrimidin-4-amine (CAS 1956334-57-8)
- (E)-N,N-dimethyl-N'-(5-(2,2,2-trifluoroacetyl)thiazol-2-yl)formimidamide (CAS 865659-50-3)
- 1-[(tert-butoxy)carbonyl]-3,3-difluoropyrrolidine-2-carboxylic acid (CAS 1822567-84-9)
- (R)-1-(tert-butoxycarbonyl)-4,4-difluoropyrrolidine-3-carboxylic acid (CAS 2381910-72-9)
- 2,5-Dichloro-N-(4-chloro-2-fluorophenyl)benzene-1-sulfonamide (CAS 546069-45-8)
- rel-((1R,2S)-2-Aminocyclopropyl)methanol hydrochloride (CAS 1374009-31-0)
- Tert-butyl 3,5-diaminopiperidine-1-carboxylate (CAS 2169565-52-8)
- [1,2,3]Triazolo[1,5-a]pyrazine (CAS 51392-75-7)
- tert-Butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydro-1,4-epiminonaphthalene-9-carboxylate (CAS 1590387-04-4)
- 2,3-Dichloro-N-isopropylaniline (CAS 54962-84-4)
- 728-40-5 2,6-Di-tert-butyl-4-nitrophenol Phenol, 2,6-bis(1,1-dimethylethyl)-4-nitro- (9CI) Phenol, 2,6-di-tert-butyl-4-nitro- Phenol, 2,6-bis(1,1-dimethylethyl)-4-nitro- 4-06-00-03493 (Beilstein Handbook Reference) AI3-25569 BAY 28589 Bayer 28589 Bayer 4889 2,6-Bis(1,1-dimethylethyl)-4-nitrophenol BRN 2056124 ENT 25,569 NSC 81682 (CAS 728-40-5)
- 4-Fluoro-3-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 2231673-29-1)
- N-(2-Cyclopropoxy-5-(trifluoromethyl)phenyl)methanesulfonamide (CAS 1243414-74-5)
- Galanin Message Associated Peptide (1-41) amide trifluoroacetate salt (CAS 132699-74-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com