2-(4-Bromo-2,3,6-trifluorophenyl)acetonitrile CAS 537033-58-2

Purity 97%+In StockPharmaceutical Standards
CAS No.537033-58-2
Molecular FormulaC8H3BrF3N
Molecular Weight250.02 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-Bromo-2,3,6-trifluorophenyl)acetonitrile CAS 537033-58-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Bromo-2,3,6-trifluorophenyl)acetonitrile.

CATO supplies 2-(4-Bromo-2,3,6-trifluorophenyl)acetonitrile (CAS 537033-58-2), a certified reference material (molecular formula C8H3BrF3N, MW 250.02 g/mol) for analytical method development and quality control.

The molecular framework of 2-(4-Bromo-2,3,6-trifluorophenyl)acetonitrile (C8H3BrF3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(4-Bromo-2,3,6-trifluorophenyl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H3BrF3N
Molecular Weight250.02 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Br-containing
Nitrogen Atoms1

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