537033-59-3 4-Bromo-2,3,6-trifluorophenylacetic acid MFCD03094472 CAS 537033-59-3
| CAS No. | 537033-59-3 |
| Molecular Formula | C8H4BrF3O2 |
| Molecular Weight | 269.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
537033-59-3 4-Bromo-2,3,6-trifluorophenylacetic acid MFCD03094472 (CAS 537033-59-3) is a high-purity analytical reference standard with the molecular formula C8H4BrF3O2 and a molecular weight of 269.02 g/mol.
The molecular framework of 537033-59-3 4-Bromo-2,3,6-trifluorophenylacetic acid MFCD03094472 (C8H4BrF3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4BrF3O2 |
| Molecular Weight | 269.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 5-Bromo-2-(trifluoromethyl)isonicotinamide (CAS 1070892-03-3)
- 2-Bromo-4-(trifluoromethoxy)benzaldehyde (CAS 1114808-87-5)
- 2-Bromo-6-(trifluoromethoxy)benzaldehyde (CAS 1114809-17-4)
- 1-(4-Bromo-2-hydroxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 1184850-45-0)
- 1-(5-Bromo-2-hydroxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 1190130-82-5)
- 2-Bromo-6-(trifluoromethyl)nicotinamide (CAS 1214332-09-8)
- 4-Bromo-3-(trifluoromethoxy)benzaldehyde (CAS 1221716-04-6)
- 3-Bromo-2-(trifluoromethyl)benzoic acid (CAS 1227605-02-8)
Recommended Standards
- N-(6-bromopyridin-2-yl)-2,2,2-trifluoroacetamide (CAS 845658-84-6)
- 3-(Difluoromethyl)-2-iodoaniline (CAS 1261454-56-1)
- N-(5-Bromopyridin-2-yl)-2,2,2-trifluoroacetamide (CAS 207926-35-0)
- 2-(Difluoromethyl)-5-iodoaniline (CAS 1261479-80-4)
- (4-chloro-2-iodophenyl)methanamine hydrochloride (CAS 1790156-20-5)
- 2,4-Dimethylanisole (CAS 6738-23-4)
- 2-((4,5-Diphenyloxazol-2-yl)thio)-N-isobutylpropanamide (CAS 1280298-31-8)
- 5-Cyclopropoxy-2-isopropoxyisonicotinonitrile (CAS 1243372-56-6)
- 3-(3-(Dimethylamino)propoxy)benzaldehyde (CAS 26815-13-4)
- 2-Ethynyl-1,3-difluorobenzene (CAS 381723-16-6)
- 2-Chloro-5-((trimethylsilyl)ethynyl)pyridin-4-amine (CAS 1296201-72-3)
- 4-((5-(Trifluoromethyl)pyridin-2-yl)oxy)benzamide (CAS 1024143-17-6)
- Methyl 2,5-dichlorothiazole-4-carboxylate (CAS 135925-32-5)
- Peptide 442 (CAS CATO-CPTD788442)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com