7-Fluoro-4-methoxy-6-methyl-2-(trifluoromethyl)quinoline CAS 537033-77-5

Purity 97%+In StockPharmaceutical Standards
CAS No.537033-77-5
Molecular FormulaC12H9F4NO
Molecular Weight259.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Fluoro-4-methoxy-6-methyl-2-(trifluoromethyl)quinoline CAS 537033-77-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Fluoro-4-methoxy-6-methyl-2-(trifluoromethyl)quinoline.

7-Fluoro-4-methoxy-6-methyl-2-(trifluoromethyl)quinoline (CAS 537033-77-5) is a high-purity analytical reference standard with the molecular formula C12H9F4NO and a molecular weight of 259.20 g/mol.

The molecular framework of 7-Fluoro-4-methoxy-6-methyl-2-(trifluoromethyl)quinoline (C12H9F4NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 7-Fluoro-4-methoxy-6-methyl-2-(trifluoromethyl)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H9F4NO
Molecular Weight259.20 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF-containing
Nitrogen Atoms1

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