4-(2-Bromophenyl)-N-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide CAS 537679-00-8
| CAS No. | 537679-00-8 |
| Molecular Formula | C18H15BrFN3O2 |
| Molecular Weight | 404.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(2-Bromophenyl)-N-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 537679-00-8), molecular formula C18H15BrFN3O2 and molecular weight 404.23 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(2-Bromophenyl)-N-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (C18H15BrFN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 404.23 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(2-Bromophenyl)-N-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15BrFN3O2 |
| Molecular Weight | 404.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromophenyl Standards
- 3-(5-(4-Bromophenyl)furan-2-yl)-2-(furan-2-ylsulfonyl)acrylonitrile (CAS 853407-08-6)
- 4-(4-Bromophenyl)-N-(2-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 893680-50-7)
- N-(2-((4-bromophenyl)sulfonyl)ethyl)-2,6-difluorobenzamide (CAS 338956-11-9)
- N-{2-[(4-bromophenyl)sulfanyl]ethyl}-3-(trifluoromethyl)benzamide (CAS 338956-08-4)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(m-tolyl)acetamide (CAS 332114-25-7)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(o-tolyl)acetamide (CAS 332114-24-6)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(p-tolyl)acetamide (CAS 332114-26-8)
- 2-((5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(o-tolyl)acetamide (CAS 336174-52-8)
Recommended Standards
- 3-Methyl-4-(2,2,3,3,4,4,5,5,5-nonafluoropentyl)cyclopentane-1,1-dicarboxylic acid (CAS 20116-32-9)
- 3-Chloro-N-(2-chloro-5-(trifluoromethyl)phenyl)-6-methylbenzo[b]thiophene-2-carboxamide (CAS 332382-28-2)
- Tert-butyl 3-(((3-iodopyridin-4-yl)oxy)methyl)pyrrolidine-1-carboxylate (CAS 1171920-04-9)
- 2-Chloro-4-(3-(3-methyl-4-nitrophenyl)ureido)benzene-1-sulfonyl chloride (CAS 680617-73-6)
- 3-Hydroxy-2-nitrobenzonitrile (CAS 129298-23-3)
- tert-butyl N-(5-oxohexyl)carbamate (CAS 153495-58-0)
- 2-Butoxy-4-methoxybenzoic acid (CAS 95420-80-7)
- 5-Amino-n,n-dimethyl-1-benzofuran-2-carboxamide (CAS 1002726-97-7)
- FLAVANONE HYDRAZONE (CAS 1692-46-2)
- Thiamine Impurity 25 (CAS 2169341-54-0)
- 4-(4-Iodo-1h-pyrazol-1-yl)-3-methylbenzaldehyde (CAS 1341050-98-3)
- 1,2,3,5-Tetramethylbenzene-d14 (CAS 1219795-11-5)
- (S)-3,3'-Bis(4-trifluoromethylphenyl)-1,1'-binaphthyl-2,2'-disulfonimide (CAS 1644388-85-1)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com