3-Bromo-5-phenyl-1H-pyrazolo[3,4-b]pyridine CAS 537678-51-6
| CAS No. | 537678-51-6 |
| Molecular Formula | C12H8BrN3 |
| Molecular Weight | 274.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Bromo-5-phenyl-1H-pyrazolo[3,4-b]pyridine (CAS 537678-51-6), a certified reference material (molecular formula C12H8BrN3, MW 274.12 g/mol) for analytical method development and quality control.
The molecular framework of 3-Bromo-5-phenyl-1H-pyrazolo[3,4-b]pyridine (C12H8BrN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 3-Bromo-5-phenyl-1H-pyrazolo[3,4-b]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8BrN3 |
| Molecular Weight | 274.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 7-Bromo-3-phenyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1021923-08-9)
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- 6-Bromo-8-phenylimidazo[1,2-a]pyrazine (CAS 1159815-57-2)
- 6-Bromo-8-phenyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1202277-96-0)
- 6-Bromo-3-phenyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1260810-02-3)
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Recommended Standards
- 3-Bromo-2-phenylimidazo[1,2-b]pyridazine (CAS 802580-12-7)
- 3-Chloro-5-(2-chlorophenyl)isothiazole-4-carboxylic acid (CAS 306935-52-4)
- 3-Bromo-2-phenylimidazo[1,2-a]pyrimidine (CAS 904814-72-8)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (2,5-dimethoxy-2,5-dihydrofuran-3-yl)boronate (CAS 2223003-40-3)
- 4-[(2E)-3-(2-Chlorophenyl)prop-2-enoyl]phenyl 4-tert-butylbenzoate (CAS 331461-31-5)
- Tetrakis(dimethylsilyl)silane (CAS 2003-85-2)
- N-(2,2-dimethylthietan-3-yl)-2-hydroxypropanamide (CAS 1880816-24-9)
- Dinoterb (CAS 1420-07-1)
- 3-Cyclohexyl-1-methyl-1H-pyrazol-5-ol (CAS 61199-34-6)
- N-Cyclopropyl-2-mercaptoquinoline-4-carboxamide (CAS 875160-00-2)
- 2-Nitrodibenzo[b,f][1,4]oxazepin-11(10H)-one (CAS 16398-16-6)
- Isoquinonline-8-boronic acid pinacol ester (CAS 2379560-77-5)
- Tadalafil Impurity 24 (CAS 951661-81-7)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com