4-Methoxy-2-(trifluoromethyl)aniline CAS 53903-49-4
| CAS No. | 53903-49-4 |
| Molecular Formula | C8H8F3NO |
| Molecular Weight | 191.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Methoxy-2-(trifluoromethyl)aniline (CAS 53903-49-4), a certified reference material (molecular formula C8H8F3NO, MW 191.15 g/mol) for analytical method development and quality control.
4-Methoxy-2-(trifluoromethyl)aniline (C8H8F3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 4-Methoxy-2-(trifluoromethyl)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8F3NO |
| Molecular Weight | 191.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- 106877-20-7 3-Methoxy-4-(trifluoromethyl)phenylamine MFCD11840978 (CAS 106877-20-7)
- 2-Methoxy-3-methyl-5-(trifluoromethyl)pyridine (CAS 124432-64-0)
- 2-Methoxy-6-(trifluoromethyl)aniline (CAS 133863-87-3)
- 2-Methoxy-6-methyl-4-(trifluoromethyl)pyridine (CAS 1379091-35-6)
- 2-Methoxy-4-(trifluoromethyl)aniline (CAS 158727-56-1)
- 3-Methoxy-6-methyl-2-(trifluoromethyl)pyridine (CAS 1956340-30-9)
- 2-methoxy-3-(trifluoromethyl)aniline (CAS 634187-08-9)
- 2-Methoxy-4-methyl-5-(trifluoromethyl)pyridine (CAS 247573-70-2)
Recommended Standards
- 4,5,6,7-Tetrahydro-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 743419-80-9)
- 4-Methyl-3-(trifluoromethoxy)aniline (CAS 851045-64-2)
- 4-(Trifluoromethyl)-2-pyrimidineethanamine (CAS 944898-59-3)
- 4-Nitro-2-(1H-1,2,4-triazol-1-yl)pyridine (CAS 942076-78-0)
- 4-(Chloromethyl)thiazole-2-carbonyl chloride (CAS 200418-16-2)
- (4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)urea (CAS 339023-79-9)
- 5-Cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole-4-carboxylic acid (CAS 2191433-23-3)
- 1-Methyl-3-propyl-2-thiobarbituricacid (CAS 57481-65-9)
- rel-(3R,4R)-3-Amino-4-hydroxytetrahydrothiophene 1,1-dioxide (CAS 20688-37-3)
- 3-[(4-Methylbenzyl)oxy]pyrrolidine hydrochloride (CAS 1185176-09-3)
- 1-(2-Benzoylphenyl)-1H-pyrrole (CAS 63477-89-4)
- 3-(4-Chloro-2-methyl-5-nitrophenoxymethyl)pyridine (CAS 1881320-50-8)
- Decafluorobiphenyl (CAS 434-90-2)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com