4-Hydroxy-7-(trifluoromethoxy)quinoline-3-carboxylic acid CAS 53985-74-3
| CAS No. | 53985-74-3 |
| Molecular Formula | C11H6F3NO4 |
| Molecular Weight | 273.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 273.16 g/mol gives 4-Hydroxy-7-(trifluoromethoxy)quinoline-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Hydroxy-7-(trifluoromethoxy)quinoline-3-carboxylic acid (CAS 53985-74-3) is a high-purity analytical reference standard with the molecular formula C11H6F3NO4 and a molecular weight of 273.16 g/mol.
Based on its molecular formula C11H6F3NO4, 4-Hydroxy-7-(trifluoromethoxy)quinoline-3-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 273.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Hydroxy-7-(trifluoromethoxy)quinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H6F3NO4 |
| Molecular Weight | 273.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 4-Hydroxy-6-(trifluoromethoxy)quinoline-3-carboxylic acid (CAS 175203-86-8)
- 6-Hydroxy-2-((5-nitrofuran-2-yl)methylene)benzofuran-3(2H)-one (CAS 17817-38-8)
- 3,3'-((6-Hydroxy-1,3,5-triazine-2,4-diyl)bis(oxy))dipropionic acid (CAS 2904-40-7)
- 3-Hydroxy-2,4,6-trinitrobenzoic acid (CAS 33927-45-6)
- 3-Hydroxy-4-nitro-benzoic Acid Phenylmethyl Ester (CAS 123015-42-9)
- Benzyl 2-Hydroxy-5-nitrobenzoate (CAS 155388-71-9)
- 3-Hydroxy-N-(4-methylpyridin-3-yl)-4-nitrobenzamide (CAS 1797793-89-5)
- 4-Hydroxy-7-isopropoxy-6-nitroquinoline-3-carbonitrile (CAS 919482-01-2)
Recommended Standards
- 2-Fluoro-1-nitro-4-((trifluoromethyl)sulfonyl)benzene (CAS 2149601-78-3)
- 4-Oxo-8-(trifluoromethoxy)-1,4-dihydroquinoline-3-carboxylic acid (CAS 40516-40-3)
- 2-Chloro-1-[4-(3-chlorophenyl)piperazin-1-yl]ethan-1-one (CAS 70395-06-1)
- 5-(4-(Trifluoromethoxy)phenyl)oxazole-4-carboxylic acid (CAS 887267-64-3)
- 4-chloro-7-fluoro-9H-pyrimido[4,5-b]indole (CAS 1909318-74-6)
- 2-(((4aR,6S,7R,8R,8aS)-7-Acetamido-6-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)acetic acid (CAS 14595-22-3)
- Tert-butyl (8S)-6-amino-5,7,7-tricyano-8-(4-(trifluoromethyl)phenyl)-3,7,8,8a-tetrahydroisoquinoline-2(1H)-carboxylate (CAS 1212459-44-3)
- 5-Methylpyrazolo[1,5-a]pyrimidin-7-ol (CAS 16082-26-1)
- 4-Fluoro-1-(piperidin-4-yl)-1h-benzo[d]imidazole hydrochloride (CAS 2490698-43-4)
- Ethyl 3-amino-2,6-dibromo-4-chlorobenzoate (CAS 1208077-33-1)
- N-(Pyridin-3-ylmethyl)hydroxylamine (CAS 851287-13-3)
- Pipracil (CAS 61477-96-1)
- 8-Bromo-5-fluoroisoquinolin-3-amine (CAS 1221974-48-6)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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