5-Chloro-3-((4-fluorophenyl)thio)-1H-indole-2-carboxamide CAS 540740-76-9
| CAS No. | 540740-76-9 |
| Molecular Formula | C15H10ClFN2OS |
| Molecular Weight | 320.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-3-((4-fluorophenyl)thio)-1H-indole-2-carboxamide.
5-Chloro-3-((4-fluorophenyl)thio)-1H-indole-2-carboxamide (CAS 540740-76-9), molecular formula C15H10ClFN2OS and molecular weight 320.77 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-3-((4-fluorophenyl)thio)-1H-indole-2-carboxamide (C15H10ClFN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-3-((4-fluorophenyl)thio)-1H-indole-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10ClFN2OS |
| Molecular Weight | 320.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 6-Isopropyl-2-methylimidazo[1,5-a]pyrimidin-4(1H)-one (CAS 79899-02-8)
- 4'-Methyl-2,3,4,5-tetrahydro-1,1'-biphenyl (CAS 1821-23-4)
- 8-Chloro-6-fluoro-4-hydroxyquinoline-3-carboxylic acid (CAS 1019015-99-6)
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