5-Chloro-3-((4-chlorophenyl)thio)-1H-indole-2-carboxamide CAS 540740-77-0
| CAS No. | 540740-77-0 |
| Molecular Formula | C15H10Cl2N2OS |
| Molecular Weight | 337.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-3-((4-chlorophenyl)thio)-1H-indole-2-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-3-((4-chlorophenyl)thio)-1H-indole-2-carboxamide (CAS 540740-77-0), molecular formula C15H10Cl2N2OS and molecular weight 337.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-3-((4-chlorophenyl)thio)-1H-indole-2-carboxamide (C15H10Cl2N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-3-((4-chlorophenyl)thio)-1H-indole-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10Cl2N2OS |
| Molecular Weight | 337.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- (2E)-7-Chloro-2-{[(2-chlorophenyl)amino]methylidene}-3,4-dihydro-2H-1,4-benzothiazin-3-one (CAS 338417-08-6)
- (2E)-7-Chloro-2-{[(3-chlorophenyl)amino]methylidene}-3,4-dihydro-2H-1,4-benzothiazin-3-one (CAS 338417-09-7)
- (2E)-7-Chloro-2-{[(4-chlorophenyl)amino]methylidene}-3,4-dihydro-2H-1,4-benzothiazin-3-one (CAS 338417-14-4)
- 2-Chloro-1-[4-(2-chlorobenzenesulfonyl)piperazin-1-yl]ethan-1-one (CAS 923756-84-7)
- 2-Chloro-1-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]ethanone (CAS 731011-99-7)
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Recommended Standards
- 4-Methyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzamide (CAS 2246890-53-7)
- 5-Methylcytidylic acid (CAS 3590-36-1)
- 4-Methyl-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzamide (CAS 2246615-20-1)
- N-(2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzamide (CAS 2095280-78-5)
- 1-(Methylsulfanyl)cyclobutane-1-carbaldehyde (CAS 35120-17-3)
- 5-(4-Chlorophenyl)pyrimidine-2,4-diol (CAS 116659-59-7)
- 1-(4-(Pentylthio)phenyl)ethan-1-ol (CAS 1410041-04-1)
- 2-Cyanophenylzinc bromide 0.5 M in Tetrahydrofuran (CAS 131379-17-4)
- 3-Ethoxy-5-(4-methoxyphenyl)-1H-1,2,4-triazole (CAS 62036-07-1)
- Ethyl 2,2-difluoro-2-(6-methoxypyridin-2-yl)acetate (CAS 503627-75-6)
- Kaurene (CAS 34424-57-2)
- Alogliptin Impurity 2 (CAS CATO-C4X-10992)
- Cyclohexanol-d12 (CAS 66522-78-9)
- Des-Ile12-Aib13-Tirzepatide (CAS CATO-CPTD788960)
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