3-Iodo-2-nitropyridine CAS 54231-34-4
| CAS No. | 54231-34-4 |
| Molecular Formula | C5H3IN2O2 |
| Molecular Weight | 249.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Iodo-2-nitropyridine.
3-Iodo-2-nitropyridine (CAS 54231-34-4) is a high-purity analytical reference standard with the molecular formula C5H3IN2O2 and a molecular weight of 249.99 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, 3-Iodo-2-nitropyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 249.99 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H3IN2O2 |
| Molecular Weight | 249.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Iodo Standards
- 4-Iodo-2-nitropyridine (CAS 1003711-88-3)
- 4-Iodo-3-nitropyridine (CAS 1003711-92-9)
- 5-Iodo-2-nitropyridine (CAS 125261-86-1)
- 2-Iodo-3-nitropyridine (CAS 209286-96-4)
- 2-Iodo-4-nitropyridine (CAS 89283-69-2)
- 3-Iodo-4-nitropyridine (CAS 89283-70-5)
- 3-Iodo-5-nitropyridine (CAS 25391-55-3)
- 2-Iodo-6-methoxyphenol (CAS 111726-46-6)
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- tert-Butyl 2-benzylpiperazine-1-carboxylate (CAS 481038-63-5)
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- 2-(3,4-Dimethoxyphenyl)-4-pentyn-2-ol (CAS 2006278-36-8)
- 1,4-Diazabicyclo[2.2.2]octane 4-methylbenzenesulfonate (CAS 34985-57-4)
- Methyl 2-amino-4-methylnicotinate (CAS 76336-16-8)
- 4-(6-Methylpyrazin-2-yloxy)benzamide (CAS 2140305-86-6)
- 6-(sec-Butoxy)-2-((3,5-dimethylphenyl)sulfonyl)pyrimidin-4-amine (CAS 284681-60-3)
- Neuropeptide S (human) (CAS 412938-67-1)
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