2-Chloro-5-hydroxy-3-methylpyridine CAS 54232-03-0
| CAS No. | 54232-03-0 |
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-5-hydroxy-3-methylpyridine (CAS 54232-03-0), molecular formula C6H6ClNO and molecular weight 143.57 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Chloro-5-hydroxy-3-methylpyridine (C6H6ClNO) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 143.57 g/mol, it falls into the low-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-6-methylpyridin-2-ol (CAS 103997-23-5)
- N-(3-Chloro-phenyl)hydroxylamine (CAS 10468-17-4)
- (5-Chloro pyrazin-2-yl) Methanamine (CAS 1060814-53-0)
- 4-Chloro-3-methylpyridine 1-Oxide (CAS 1073-34-3)
- 2-Chloro-3-hydrazinylpyridine (CAS 117087-45-3)
- 5-Chloro-2-methylpyridin-4(1H)-one (CAS 1196157-19-3)
- 2-Chloro-1-(1H-pyrrol-3-yl)ethanone (CAS 122450-28-6)
- 3-Chloro-2-methylpyridin-4-ol (CAS 1227499-23-1)
Recommended Standards
- 2-CHLORO-4-METHYLPYRIDINE 1-OXIDE (CAS 52313-61-8)
- 2-Chloro-5-methylpyridine 1-oxide (CAS 20173-49-3)
- 2-Chloro-4-methylpyridin-3-ol (CAS 884494-70-6)
- 2-Chloro-5-pyridinemethanol (CAS 21543-49-7)
- 1,3-Dibromo-5-isobutoxybenzene (CAS 918904-37-7)
- 2-(4-Bromo-3-methylphenoxy)benzaldehyde (CAS 882747-77-5)
- tert-Butyl (3-hydroxy-1-(o-tolyl)propyl)carbamate (CAS 862466-17-9)
- N,9-Diethyl-6-methyl-9H-purin-2-amine (CAS 685081-72-5)
- (2E)-1-(4-Ethylphenyl)-3-(3-methylphenyl)prop-2-en-1-one (CAS 1176632-70-4)
- 4H-1,2,4-triazole-3,4-diamine hydrochloride (CAS 6421-05-2)
- 90833-53-7 2,3-Bis(4-chlorophenyl)quinoxaline-6-carboxylic acid MFCD00555191 (CAS 90833-53-7)
- Indoline-5-boronic acid pinacol ester, 97% (CAS 1062174-44-0)
- 1,2:5,6-Diisopropylidene-3-O-methyl-α-D-glucofuranose (CAS 43138-64-3)
- D-Pro36-Tirzepatide (CAS CATO-CPTD788903)
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