(3E,5E)-3,5-Bis[(3-chlorophenyl)methylidene]-1-methylpiperidin-4-one CAS 54237-29-5

Purity 97%+In StockPharmaceutical Standards
CAS No.54237-29-5
Molecular FormulaC20H17Cl2NO
Molecular Weight358.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3E,5E)-3,5-Bis[(3-chlorophenyl)methylidene]-1-methylpiperidin-4-one CAS 54237-29-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 358.26 g/mol gives (3E,5E)-3,5-Bis[(3-chlorophenyl)methylidene]-1-methylpiperidin-4-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(3E,5E)-3,5-Bis[(3-chlorophenyl)methylidene]-1-methylpiperidin-4-one (CAS 54237-29-5), molecular formula C20H17Cl2NO and molecular weight 358.26 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (3E,5E)-3,5-Bis[(3-chlorophenyl)methylidene]-1-methylpiperidin-4-one (C20H17Cl2NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (3E,5E)-3,5-Bis[(3-chlorophenyl)methylidene]-1-methylpiperidin-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC20H17Cl2NO
Molecular Weight358.26 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972
Halogen ContentCl-containing
Nitrogen Atoms1

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