Dotinurad Impurity 225 CAS CATO-C4X-2494225
| CAS No. | CATO-C4X-2494225 |
| Molecular Formula | C17H13Cl2NO3S |
| Molecular Weight | 382.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 382.26 g/mol gives Dotinurad Impurity 225 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Dotinurad Impurity 225 (CAS CATO-C4X-2494225) is a certified pharmaceutical impurity reference standard with the molecular formula C17H13Cl2NO3S and a molecular weight of 382.26 g/mol.
The molecular framework of Dotinurad Impurity 225 (C17H13Cl2NO3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dotinurad Impurity 225 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H13Cl2NO3S |
| Molecular Weight | 382.26 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dotinurad Standards
- Dotinurad Impurity 156 (CAS CATO-C4X-2494156)
- Dotinurad Impurity 13 (CAS CATO-C4X-249413)
- Dotinurad Impurity 162 (CAS CATO-C4X-2494162)
- Dotinurad Impurity 146 (CAS CATO-C4X-2494146)
- Dotinurad Impurity 246 (CAS CATO-C4X-2494246)
- Dotinurad impurity 108 (CAS CATO-C4X-2494108)
- Dotinurad Impurity 187 (CAS CATO-C4X-2494187)
- Dotinurad Impurity 60 (CAS CATO-C4X-249460)
Recommended Standards
- Crisaborole impurity 160 (CAS CATO-C4X-2021160)
- 5-Bromo-3'-(pyrrolidin-1-ylsulfonyl)-[1,1'-biphenyl]-3-ol (CAS 1261902-92-4)
- N-(3-chloro-4-fluorophenyl)-2-(4-(3-chlorophenyl)piperazin-1-yl)acetamide (CAS 329079-88-1)
- 5-Bromo-4'-(pyrrolidin-1-ylsulfonyl)-[1,1'-biphenyl]-3-ol (CAS 1262004-08-9)
- Clonazepam Impurity 22 (CAS 16346-60-4)
- Folic Acid EP Impurity D (CAS 119-24-4)
- Pyridoxine Impurity 45 HCl (CAS 19203-53-3(Free base))
- 5-Nitro-1-phenyl-1H-benzimidazole (CAS 15127-88-5)
- 2-(1-oxo-1,2-dihydroisoquinolin-2-yl)propanoic acid (CAS 344461-41-2)
- 2-((1-(Pyridin-4-yl)ethyl)amino)propane-1,3-diol (CAS 1462829-87-3)
- 4-(Trifluoromethoxy)benzo[d]isoxazol-3-amine (CAS 1228574-43-3)
- 8-bromo-N-tert-butyl-1,5-naphthyridin-2-amine (CAS 2891473-59-7)
- (2-Phenylbenzo[d]oxazol-4-yl)methanamine (CAS 760111-76-0)
- Anti-Inflammatory Peptide 3 (CAS 118850-73-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com