Abemaciclib Impurity 140 CAS 2124229-65-6
| CAS No. | 2124229-65-6 |
| Molecular Formula | C18H31N5 |
| Molecular Weight | 317.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Abemaciclib Impurity 140 (CAS 2124229-65-6), a pharmacopoeial impurity reference standard (molecular formula C18H31N5, MW 317.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H31N5, Abemaciclib Impurity 140 contains a nitrogen-containing heterocyclic scaffold, a nitrile group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 317.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Abemaciclib Impurity 140 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H31N5 |
| Molecular Weight | 317.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 5 |
Related Abemaciclib Standards
- Abemaciclib Impurity N7 (CAS 1231930-37-2)
- Abemaciclib Impurity N3 (CAS 1231930-42-9)
- Abemaciclib Impurity 4 (CAS CATO-C4X-29374)
- Abemaciclib Impurity N1 (CAS 2177297-46-8)
- Abemaciclib Impurity 177 (CAS CATO-C4X-2937177)
- Abemaciclib Impurity 167 (CAS CATO-C4X-2937167)
- Abemaciclib Impurity 69 (CAS 1873303-32-2)
- Abemaciclib Impurity 70 (CAS 1231930-47-4)
Recommended Standards
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- Niraparib Impurity 38 (CAS CATO-C4X-232938)
- Terbutaline Impurity 77 (CAS CATO-C4X-118377)
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- (S)-1-(4-Methoxypyridin-2-yl)ethanamine dihydrochloride (CAS 2566633-11-0)
- 3-Azabicyclo[3.2.2]nonane (CAS 283-24-9)
- 4-((4,6-Dimethoxypyrimidin-2-yl)oxy)benzaldehyde (CAS 491871-36-4)
- N-(2-(Diethylamino)ethyl)-3-oxobutanamide (CAS 590424-03-6)
- Azithromycin impurity 57 (CAS CATO-C4X-100357)
- 1-(Furan-3-carbonyl)piperidin-4-amine (CAS 926210-83-5)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com