2-Iodo-6-nitro-4-(trifluoromethyl)aniline CAS 543740-74-5
| CAS No. | 543740-74-5 |
| Molecular Formula | C7H4F3IN2O2 |
| Molecular Weight | 332.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Iodo-6-nitro-4-(trifluoromethyl)aniline (CAS 543740-74-5), a certified reference material (molecular formula C7H4F3IN2O2, MW 332.02 g/mol) for analytical method development and quality control.
2-Iodo-6-nitro-4-(trifluoromethyl)aniline (C7H4F3IN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Iodo-6-nitro-4-(trifluoromethyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4F3IN2O2 |
| Molecular Weight | 332.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Iodo Standards
- 3-Iodo-4-(trifluoromethoxy)benzoic acid (CAS 1110709-70-0)
- 2-Iodo-4-nitro-5-(trifluoromethyl)aniline (CAS 852569-37-0)
- 2-Iodo-4-nitro-6-(trifluoromethyl)aniline (CAS 400-69-1)
- 4-Iodo-3-(trifluoromethoxy)benzoic acid (CAS 886762-67-0)
- Methyl 3-iodo-5-methoxy-2H-indazole-6-carboxylate (CAS 1227270-54-3)
- Ethyl 6-iodo-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-1-carboxylate (CAS 161468-54-8)
- 3-Iodo-5,7-dimethoxy-4H-chromen-4-one (CAS 187877-91-4)
- (2-Iodo-6-(piperidin-3-yl)pyridin-4-yl)boronic acid (CAS 2225151-62-0)
Recommended Standards
- 4-((4-Bromophenoxy)methyl)-1,2-dichlorobenzene (CAS 889071-55-0)
- 2-Hydroxy-3-iodo-5-(trifluoromethoxy)benzaldehyde (CAS 775330-11-5)
- 1-(5-Fluoro-2-iodo-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 2090944-95-7)
- 2-(Benzyloxy)-1-bromo-3,5-dichlorobenzene (CAS 2624417-12-3)
- N-(3,4-dimethoxyphenethyl)thiophene-2-carboxamide (CAS 98215-46-4)
- 2-(3-Chloro-4-(methylsulfonyl)phenyl)-3-((S)-3-oxocyclopentyl)-N-(pyrazin-2-yl)propanamide (CAS 625114-41-2)
- 5-(3-Methoxyphenyl)-1,2,3,6-tetrahydropyridine (CAS 88593-63-9)
- 3-Methyl-5-(methylthio)benzaldehyde (CAS 1289089-92-4)
- 2,4-Dimethyl-6-((3-methylcyclobutyl)methoxy)benzaldehyde (CAS 1707393-26-7)
- 5-Methyl-2-(trifluoromethyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one (CAS 198953-53-6)
- Methyl benzothiophene-3-carboxylate (CAS 22913-25-3)
- 2,6-dinitrophenyl methyl ether (CAS 3535-67-9)
- 1-(1h-Pyrazol-1-yl)-N-(thiazol-4-ylmethyl)propan-2-amine (CAS 1250321-21-1)
- Semaglutide Impurity 6 (CAS 62-57-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com