4-Chloro-6-phenylquinoline CAS 5443-23-2
| CAS No. | 5443-23-2 |
| Molecular Formula | C12H8ClNO2 |
| Molecular Weight | 233.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 233.65 g/mol gives 4-Chloro-6-phenylquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-6-phenylquinoline (CAS 5443-23-2), molecular formula C12H8ClNO2 and molecular weight 233.65 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Chloro-6-phenylquinoline (C12H8ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 233.65 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-6-phenylquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClNO2 |
| Molecular Weight | 233.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro(pyridin-4-yl)pyridine-2-carboxamide (CAS 1026136-67-3)
- 6-Chloro-N-pyridin-4-ylnicotinamide (CAS 1090481-07-4)
- 2-Chloro-5-(pyridin-2-yl)benzoic acid (CAS 1143024-51-4)
- 5-Chloro-6-phenylpyridine-3-carboxylic acid (CAS 1148027-23-9)
- 2-Chloro-5-phenylnicotinic acid (CAS 117449-73-7)
- 2-Chloro-5-(pyridin-3-yl)benzoic acid (CAS 1178054-55-1)
- 3-Chloro-6-phenylpyridazine-4-carboxamide (CAS 118269-69-5)
- 2-Chloro-5-phenylisonicotinic acid (CAS 1214323-23-5)
Recommended Standards
- 4-Chloro-6-(furan-2-yl)-5-methyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 871025-17-1)
- 4-Chloro-7-methoxy-5H-pyrimido[5,4-b]indole (CAS 676602-23-6)
- 4'-Chloro-2-nitro-1,1'-biphenyl (CAS 6271-80-3)
- 4-Chloro-8-methoxy-5H-pyrimido[5,4-b]indole (CAS 98792-03-1)
- MEthyl 4-bromo-6-azaindole-3-carboxylate (CAS 1234616-10-4)
- (S)-4-Cyclohexyl-2-(2-(diphenylphosphanyl)phenyl)-4,5-dihydrooxazole (CAS 2634687-58-2)
- 2-Hydroxycyclohexane-1-sulfonamide (CAS 1398626-74-8)
- 1-bromo-2-pentyne (CAS 16400-32-1)
- tert-butyl (3R,4R)-3-acetoxy-4-azido-pyrrolidine-1-carboxylate (CAS 1214272-51-1)
- 2-(N-methylacetamido)butanoic acid (CAS 114126-84-0)
- N-(4-hydroxy-2-oxo-2H-chromen-3-yl)acetamide (CAS 13948-45-3)
- 2-(Tetrahydro-4H-thiopyran-4-ylidene)acetic acid (CAS 1098433-02-3)
- 2-Chloro-1-(3,5-dichlorophenyl)-2,2-difluoroethan-1-one (CAS 864725-56-4)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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