(2Z,2'Z)-4,4'-(Naphthalene-1,5-diylbis(azanediyl))bis(4-oxobut-2-enoic acid) CAS 5443-26-5

Purity 97%+In StockPharmaceutical Standards
CAS No.5443-26-5
Molecular FormulaC18H14N2O6
Molecular Weight354.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2Z,2'Z)-4,4'-(Naphthalene-1,5-diylbis(azanediyl))bis(4-oxobut-2-enoic acid) CAS 5443-26-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2Z,2'Z)-4,4'-(Naphthalene-1,5-diylbis(azanediyl))bis(4-oxobut-2-enoic acid).

(2Z,2'Z)-4,4'-(Naphthalene-1,5-diylbis(azanediyl))bis(4-oxobut-2-enoic acid) (CAS 5443-26-5), molecular formula C18H14N2O6 and molecular weight 354.31 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (2Z,2'Z)-4,4'-(Naphthalene-1,5-diylbis(azanediyl))bis(4-oxobut-2-enoic acid) (C18H14N2O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2Z,2'Z)-4,4'-(Naphthalene-1,5-diylbis(azanediyl))bis(4-oxobut-2-enoic acid) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H14N2O6
Molecular Weight354.31 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Nitrogen Atoms2

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