3-((4-Methylpiperazin-1-yl)methyl)-1h-indole CAS 5444-91-7
| CAS No. | 5444-91-7 |
| Molecular Formula | C16H23NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 297.82 g/mol gives 3-((4-Methylpiperazin-1-yl)methyl)-1h-indole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-((4-Methylpiperazin-1-yl)methyl)-1h-indole (CAS 5444-91-7), a certified reference material (molecular formula C16H23NO2HCl, MW 297.82 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 3-((4-Methylpiperazin-1-yl)methyl)-1h-indole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 297.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-((4-Methylpiperazin-1-yl)methyl)-1h-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H23NO2 HCl |
| Molecular Weight | 297.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methylpiperazin Standards
- 3-(1-Methylpiperazin-4-yl)-4-methylsulfonylaniline (CAS 1000018-41-6)
- 1-(4-Methylpiperazin-1-yl)pentan-1-one (CAS 10001-06-6)
- 1000577-07-0 5-ethyl-1-methylpiperazin-2-one (CAS 1000577-07-0)
- 1-ethyl-5-methylpiperazin-2-one (CAS 1000577-11-6)
- 4-[(4-methylpiperazin-1-yl)carbonyl]benzonitrile (CAS 1000932-49-9)
- 4-[2-(4-methylpiperazin-1-yl)ethoxy]phenol (CAS 100221-01-0)
- (5-(4-Methylpiperazin-1-yl)-2-nitrophenyl)methanol (CAS 1002556-21-9)
- (4-(3-(4-Methylpiperazin-1-yl)propoxy)phenyl)boronic acid (CAS 1003028-43-0)
Recommended Standards
- 2,2-Bis(trifluoromethyl)oxazol-5(2H)-one (CAS 72681-60-8)
- (3-(3-Ethoxypropoxy)-4-methylphenyl)boronic acid (CAS 1704067-37-7)
- 12:0(2R-OH) Ceramide (CAS 1246298-44-1)
- Abemaciclib Impurity 137 (CAS CATO-C4X-2937137)
- Tigecycline Impurity 4 (CAS CATO-C4X-18604)
- 3-(4-Chlorophenyl)-5,6-dihydroimidazo[2,1-b]thiazole (CAS 40230-00-0)
- 2,6-Diphenyl-4H-pyran-4-one (CAS 1029-94-3)
- 1-(4-Chlorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-3-carbohydrazide (CAS 1987070-55-2)
- Potassium 4-(4-chlorophenyl)-5-thioxo-4,5-dihydro-1,3,4-thiadiazole-2-thiolate (CAS 1049756-11-7)
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
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