Tigecycline Impurity 4 CAS CATO-C4X-18604
| CAS No. | CATO-C4X-18604 |
| Molecular Formula | C26H32N4O8 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tigecycline Impurity 4 (CAS CATO-C4X-18604), a pharmacopoeial impurity reference standard (molecular formula C26H32N4O8C2HF3O2, MW 642.58 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tigecycline Impurity 4 (C26H32N4O8C2HF3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tigecycline Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H32N4O8 C2HF3O2 |
| Molecular Weight | 642.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Tigecycline Standards
- Tigecycline mesylate, 98% (CAS 1135871-27-0)
- Tigecycline EP Impurity D(Tigecycline USP related compound A) (CAS 1138343-10-8)
- Tigecycline Hydrate (CAS 1229002-07-6)
- Tigecycline Impurity 7 (CAS 1268494-40-1)
- Tigecycline Impurity 22 Phosphate (CAS 1268494-40-1（free base）)
- Tigecycline Impurity 9 (CAS 1268494-46-7)
- Tigecycline Impurity 23 TFA (CAS 1268494-46-7（free base）)
- Tigecycline EP Impurity A (CAS 1422262-97-2)
Recommended Standards
- Iloperidone Hydroxy Impurity (CAS 133454-55-4)
- Azithromycin EP Impurity N (CAS 612069-25-7)
- Hydrocortisone Impurity 01 (CAS 10215-75-5)
- 3-Chlorothioanisole (CAS 4867-37-2)
- ONX 0914 (CAS 960374-59-8)
- Melatonin Impurity N2 (CAS 52450-39-2)
- 4-Chlorobut-2-yn-1-yl 4-nitrobenzoate (CAS 61273-13-0)
- Tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate (CAS 2376764-47-3)
- 1-(5-Bromothiophen-2-yl)-4-methylpentane-1,3-dione (CAS 1267203-95-1)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com