Fasudil Impurity 27 CAS 5451-44-5
| CAS No. | 5451-44-5 |
| Molecular Formula | C17H20N2O4S2 |
| Molecular Weight | 380.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Fasudil Impurity 27 (C17H20N2O4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Fasudil Impurity 27 (CAS 5451-44-5) is a certified pharmaceutical impurity reference standard with the molecular formula C17H20N2O4S2 and a molecular weight of 380.48 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fasudil Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H20N2O4S2 |
| Molecular Weight | 380.48 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Fasudil Standards
Recommended Standards
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- Vinpocetine EP Impurity C (CAS 70155-05-4)
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- tert-butyl 2-bromo-2-cyclopropylacetate (CAS 2059993-81-4)
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- Benzyl 1'-methylspiro[indoline-3,4'-piperidine]-1-carboxylate (CAS 167483-90-1)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
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