Fasudil Impurity 47 CAS 105628-70-4
| CAS No. | 105628-70-4 |
| Molecular Formula | C14H16ClN3O2S |
| Molecular Weight | 325.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Fasudil Impurity 47 (C14H16ClN3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Fasudil Impurity 47 (CAS 105628-70-4) is a certified pharmaceutical impurity reference standard with the molecular formula C14H16ClN3O2S and a molecular weight of 325.81 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fasudil Impurity 47 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H16ClN3O2S |
| Molecular Weight | 325.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fasudil Standards
- Fasudil impurity 66 (CAS CATO-C4X-136566)
- Fasudil impurity 33 (CAS CATO-C4X-136562)
- Fasudil Impurity 26 (CAS 4392-52-3)
- Fasudil Hydroxy (CAS 105628-72-6)
- Fasudil Impurity 9 (CAS 1350827-92-7)
- Fasudil impurity 65 (CAS CATO-C4X-136565)
- Fasudil Impurity 14 (CAS CATO-C4X-136514)
- Fasudil Impurity 24 (CAS CATO-C4X-136524)
Recommended Standards
- tert-Butyl 7-((chlorosulfonyl)methyl)-6-oxa-2-azaspiro[3.4]octane-2-carboxylate (CAS 2137746-17-7)
- 4-((4-(4-Chloro-3-methylphenyl)thiazol-2-yl)amino)benzonitrile (CAS 1022254-59-6)
- 4-Chloro-n-(4-methoxybenzyl)-n-methylbenzenesulfonamide (CAS 923836-48-0)
- 2-((1-(3-Chloro-4-methylphenyl)-1H-tetrazol-5-yl)thio)-N-isopropylacetamide (CAS 874467-78-4)
- Nilotinib Impurity 25 (CAS 41574-91-8)
- Lansoprazole Impurity 31 (CAS CATO-C4X-111331)
- Upadacitinib Impurity 63 (CAS CATO-C4X-240563)
- Olanzapine (CAS 132539-06-1)
- Methyl 6-amino-5-cyano-2-(((3-cyano-4,6-dimethylpyridin-2-yl)thio)methyl)-4-(pyridin-3-yl)-4H-pyran-3-carboxylate (CAS 354554-90-8)
- 1-(Tert-butyl) 4-methyl 2,2-dimethylpiperidine-1,4-dicarboxylate (CAS 2113627-49-7)
- 2-Amino-6-bromo-3-fluorophenol (CAS 1805533-15-6)
- [5-methyl-1-(2-methylpropyl)-1h-pyrazol-4-yl]methanamine (CAS 1247814-97-6)
- (2,3,5,6-Tetramethylphenyl)methanol (CAS 78985-13-4)
- β-Bag Cell Peptide (Aplysia californica) (CAS 109024-47-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com