Nicardipine Impurity 47 CAS 54527-65-0
| CAS No. | 54527-65-0 |
| Molecular Formula | C14H19NO3 |
| Molecular Weight | 249.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nicardipine Impurity 47 (CAS 54527-65-0), a pharmacopoeial impurity reference standard (molecular formula C14H19NO3, MW 249.31 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Nicardipine Impurity 47 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 249.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Nicardipine Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H19NO3 |
| Molecular Weight | 249.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 1 |
Related Nicardipine Standards
- Nicardipine Impurity N2 (CAS 2134320-23-1)
- Nicardipine Impurity 52 (CAS 182798-71-6)
- Nicardipine Impurity N13 (CAS 27058-15-7)
- Nicardipine Impurity N11 (CAS 101-06-4)
- Nicardipine Impurity N12 (CAS CATO-C4X-29432)
- Nicardipine Impurity 46 (CAS CATO-C4X-171046)
- Nicardipine Impurity 55 (CAS CATO-C4X-171055)
- Nicardipine Impurity 38 (CAS CATO-C4X-171038)
Recommended Standards
- Lidocaine Impurity 73 (CAS CATO-C4X-167973)
- Indobufen Impurity 64 (CAS CATO-C4X-179264)
- N-Nitroso Lidocaine (CAS CATO-C4X-167955)
- Clemastine Impurity 31 (CAS CATO-C4X-183731)
- Venlafaxine Impurity 13 (CAS CATO-C4X-143413)
- Atropine EP Impurity G ((R)-Isomer) ((R)-(-)-Littorine) HCl (CAS 21956-47-8(free base))
- Doxorubicin Olefin Impurity (CAS CATO-C4X-203318)
- N-(5-((2-(Benzo[d]thiazol-2-ylamino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-3-phenylpropanamide (CAS 477214-92-9)
- 3-(Cyclopentyloxy)-2,4-difluorophenol (CAS 1881288-45-4)
- 4-((3-(2,5-Dimethylphenyl)-1,2,4-oxadiazol-5-yl)methoxy)benzaldehyde (CAS 1707582-37-3)
- Bupivacaine Impurity 29 (CAS 2774312-11-5)
- 5-(2-Hydroxypyrimidin-5-yl)thiophene-2-carbaldehyde (CAS 1261952-75-3)
- 4-Methoxy-5-nitro-1H-pyridin-2-one (CAS 607373-82-0)
- Influenza PR8 Hemagglutinin Peptide (110-119) (H-6312.0005) (CAS 132031-50-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com