Nicardipine Impurity 46 CAS CATO-C4X-171046
| CAS No. | CATO-C4X-171046 |
| Molecular Formula | C12H8N6 |
| Molecular Weight | 236.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Nicardipine Impurity 46 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Nicardipine Impurity 46 (CAS CATO-C4X-171046), a pharmacopoeial impurity reference standard (molecular formula C12H8N6, MW 236.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C12H8N6, Nicardipine Impurity 46 contains a nitrogen-containing heterocyclic scaffold, a nitrile group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 236.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8N6 |
| Molecular Weight | 236.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Nicardipine Standards
- Nicardipine Impurity 55 (CAS CATO-C4X-171055)
- Nicardipine Impurity N1 (CAS 10323-98-5)
- Nicardipine Impurity N11 (CAS 101-06-4)
- Nicardipine Impurity N12 (CAS CATO-C4X-29432)
- Nicardipine Impurity 52 (CAS 182798-71-6)
- Nicardipine Impurity 47 (CAS 54527-65-0)
- Nicardipine Impurity N2 (CAS 2134320-23-1)
- Nicardipine Impurity N13 (CAS 27058-15-7)
Recommended Standards
- Doxofylline Impurity 40 (CAS 23146-07-8)
- Theophylline Impurity 15 (CAS CATO-C4X-182315)
- Zolmitriptan Impurity 43 (CAS CATO-C4X-135143)
- Baricitinib Impurity 87 (CAS CATO-C4X-226087)
- Fluralaner Impurity 6 (CAS 864725-62-2)
- Tolvaptan Impurity 36 (CAS CATO-C4X-195536)
- Eravacycline impurity 24 (CAS CATO-C4X-293824)
- 1,1'-Bi[2-naphthoic acid] (CAS 99827-46-0)
- 2-(1-Methyl-1,2,3,4-tetrahydroquinolin-6-yl)acetic acid (CAS 30199-70-3)
- N-(6-acetylbenzo[d][1,3]dioxol-5-yl)-2-(4-benzhydrylpiperazin-1-yl)acetamide (CAS 491867-78-8)
- 1-((1-Isopropylpiperidin-4-yl)methyl)-3-(thiophen-2-yl)urea (CAS 1210467-86-9)
- N-(4-Methoxyphenyl)-2-(4-nitrophenoxy)acetamide (CAS 303795-97-3)
- (4AS,7aR)-4a-(aminomethyl)-1-(2-methoxyethyl)octahydro-2H-cyclopenta[b]pyridin-2-one (CAS 2165423-03-8)
- Acetyl-(Leu28·31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com