2-(4-((2-Nitrophenyl)sulfonyl)piperazin-1-yl)pyrimidine CAS 545358-46-1
| CAS No. | 545358-46-1 |
| Molecular Formula | C14H15N5O4S |
| Molecular Weight | 349.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 349.37 g/mol gives 2-(4-((2-Nitrophenyl)sulfonyl)piperazin-1-yl)pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(4-((2-Nitrophenyl)sulfonyl)piperazin-1-yl)pyrimidine (CAS 545358-46-1) is a high-purity analytical reference standard with the molecular formula C14H15N5O4S and a molecular weight of 349.37 g/mol.
The molecular framework of 2-(4-((2-Nitrophenyl)sulfonyl)piperazin-1-yl)pyrimidine (C14H15N5O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-((2-Nitrophenyl)sulfonyl)piperazin-1-yl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H15N5O4S |
| Molecular Weight | 349.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Nitrophenyl Standards
- N-(4-Nitrophenyl)-2-(piperidin-1-yl)quinazolin-4-amine (CAS 75426-53-8)
- 4-Nitrophenyl myristate (CAS 14617-85-7)
- 2-Nitrophenyl myristate (CAS 59986-46-8)
- ((2-Nitrophenyl)thio)-L-threonine (CAS 7685-70-3)
- 4-(3-(3-Nitrophenyl)acrylamido)benzene-1-sulfonyl fluoride (CAS 19188-65-9)
- 4-(3-(4-Nitrophenyl)acrylamido)benzene-1-sulfonyl fluoride (CAS 19188-66-0)
- (E)-3-(4-nitrophenyl)-1-(2,2,4-trimethylquinolin-1(2H)-yl)prop-2-en-1-one (CAS 332019-32-6)
- N-(3-nitrophenyl)-N-tosylglycine (CAS 16470-61-4)
Recommended Standards
- 1-Methyl-2-{[3-(trifluoromethyl)benzyl]sulfanyl}-1H-indole-3-carbaldehyde (CAS 338416-41-4)
- 2-(Methylthio)-N-(3-(trifluoromethyl)benzyl)quinazolin-4-amine (CAS 866137-98-6)
- (2R,3R,4S,5R)-2-(6-Amino-8-(thiophen-2-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 158555-06-7)
- 2,2,2-Trifluoro-N-[3-(4-methylpiperazin-1-yl)-3-oxo-1-(thiophen-2-yl)propyl]acetamide (CAS 861209-42-9)
- 4-[(4-Chlorophenyl)sulfanyl]-6-(morpholin-4-yl)pyrimidin-2-amine (CAS 339016-20-5)
- 5-Chloro-2-benzothiazolinone (CAS 20600-44-6)
- 2,2,2-Trifluoro-1-(2-methoxyphenyl)ethanamine (CAS 886368-62-3)
- 2,3-Dihydro-3-[1-(hydroxymethyl)propyl]-2-thioxo-4(1H)-quinazolinone (CAS 179041-13-5)
- N-(2,6-dimethylphenyl)-2-morpholinoacetamide (CAS 75549-83-6)
- 2-(3-(4-Fluorophenyl)oxetan-3-yl)ethan-1-ol (CAS 1903142-29-9)
- 2-Bromo-7-chlorobenzo[d]thiazole (CAS 3507-58-2)
- 2-(4-Ethoxyphenyl)-3-hydroxy-4H-chromen-4-one (CAS 177587-97-2)
- 5-(6-Chloropyridazin-3-yl)-3-methyl-1,2,4-oxadiazole (CAS 944808-72-4)
- Semaglutide Impurity 123 (CAS 71997-93-8)
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